Results 211 to 220 of about 17,262,511 (380)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Early Post-Thrombectomy MRI Markers: Temporal Evolution and Association With Reperfusion and Clinical Outcome. [PDF]

Neurology
Luby ML, Hsia AW, Somani S, Lomahan CA, Kim Y, Burton SP, Craft V, Thomas LC, Uche V, Dhawan A, Hildreth M, Pajunar M, Sowers B, Cabatbat R, Kline M, De Vis JB, Merino JG, Wright CB, Lynch JK, Gottesman RF, Latour LL.   +20 more
europepmc   +1 more source

Chronic graft-versus-host disease after haploidentical transplantation in aplastic anemia: Clinical characteristics, risk factors, and survival outcomes [PDF]

Minghao Lin, Shengnan Gao, Xiaojun Huang, Lanping Xu, Hai-Xia Fu, Ting-ting Han, Yuanyuan Zhang, Xiao-Dong Mo, Yuqian Sun, Yi-Fei Cheng, Yu Wang, Xiaohui Zhang, Zhengli Xu   +12 more
openalex   +1 more source

Clinical Outcomes of Conservative Treatment and Arthroscopic Repair of Rotator Cuff Tears: A Retrospective Observational Study [PDF]

, 2016
Woo Hyung Lee, Hyun Kyung, Joong Hoon Lee, Bo Ram Kim, Jee Hyun Noh, Soo Hyun Choi, Sun Gun Chung, Shi-Uk Lee, Ji Eun Choi, Seihee Kim, Min Jee Kim, Jae‐Young Lim   +11 more
openalex   +1 more source

Does change in focal lordosis after spinal fusion affect clinical outcomes in degenerative spondylolisthesis?

, 2022
Brian A. Karamian, Stephen DiMaria, Mark J. Lambrechts, Nicholas D. D’Antonio, Andrew N. Sawires, Jose A. Canseco, I. David Kaye, Barrett I. Woods, Mark F. Kurd, Jeffery A. Rihn, Joseph K. Lee, Alan S. Hilibrand, Christopher K. Kepler, Alexander R. Vaccaro, Gregory D. Schroeder   +14 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Clinical outcomes of patients with diabetes mellitus and acute myocardial infarction treated with primary angioplasty or fibrinolysis [PDF]

, 2002
Li‐Fern Hsu, K H Mak, K W Lau, L L Sim, C Chan, T H Koh, S C Chuah, R Kam, Z P Ding, W S Teo, Y L Lim   +10 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Aggressive Disease and Poor Clinical Outcome in CEBPα-Mutated Acute Myeloid Leukemia Patient. [PDF]

Clin Case Rep
Alshammari AA, AlSabbagh MO, Alshehri HM, AlSwayyed AF, Alseraye FM, Peer-Zada AA.   +5 more
europepmc   +1 more source

The Impact of Sarcopenia on Clinical Outcomes after Lumbar Decompression Surgery

Yukitoshi Shimamura, Masahiro Kanayama, Fumihiro Oha, Michihaya Kono, Shogo Fukase, Kohei Shiota, Shotaro Fukada, Tsutomu Endo, Tomoyuki Hashimoto, Norimasa Iwasaki   +9 more
openalex   +1 more source