Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Predictive factors for clinical outcome of palliative ventriculoperitoneal shunt in the treatment of leptomeningeal metastasis. [PDF]
Min L, Zhang N, Zhang Q, Zheng M, Zhu Y.
europepmc +1 more source
220. Chemotherapy in Combination with T-Cell Therapy Results in Significant Antitumor Activity and Improved Clinical Outcomes for EBV-Associated Nasopharyngeal Carcinoma [PDF]
openalex +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Defining score interpretation thresholds for clinical outcome assessments: a review of terminology and reporting recommendations. [PDF]
Flood E +7 more
europepmc +1 more source
Clinical Research (Observations, Pathophysiology & Outcomes) [PDF]
openaire +2 more sources
Use of Real-World Evidence to Characterize Clinical Outcomes in Patients Who Develop Acute Graft Versus Host Disease Undergoing Allogeneic Stem Cell Transplantation in the United States [PDF]
Mona Akbari +5 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source

