Results 91 to 100 of about 1,543,622 (248)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Use of Patterns of Service Utilization and Hierarchical Survival Analysis in Planning and Providing Care for Overdose Patients and Predicting the Time-to-Second Overdose

Knowledge
Individuals from a variety of backgrounds are affected by the opioid crisis. To provide optimal care for individuals at risk of opioid overdose and prevent subsequent overdoses, a more targeted response that goes beyond the traditional taxonomical ...
Jonas Bambi, Kehinde Olobatuyi, Yudi Santoso, Hanieh Sadri, Ken Moselle, Abraham Rudnick, Gracia Yunruo Dong, Ernie Chang, Alex Kuo   +8 more
doaj   +1 more source

Effects of Pharmacist-Led Clinical Pathway/Order Sets on Cancer Patients: A Systematic Review

, 2021
Zhiyuan Tan, Zhiheng Yu, Ken Chen, Wei Liu, Rongsheng Zhao   +4 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Analyzing Patterns of Service Utilization Using Graph Topology to Understand the Dynamic of the Engagement of Patients with Complex Problems with Health Services

BioMedInformatics
Background: Providing care to persons with complex problems is inherently difficult due to several factors, including the impacts of proximal determinants of health, treatment response, the natural emergence of comorbidities, and service system capacity ...
Jonas Bambi, Yudi Santoso, Ken Moselle, Stan Robertson, Abraham Rudnick, Ernie Chang, Alex Kuo   +6 more
doaj   +1 more source

Impact of a hospital‐wide sepsis pathway on improved quality of care and clinical outcomes in surgical patients at a comprehensive cancer centre [PDF]

, 2019
Alison Hiong, Karin Thursky, Georgina Venn, Benjamin W. Teh, Gabrielle M. Haeusler, Megan Crane, Monica A. Slavin, Leon J. Worth   +7 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Exploring Acute Pancreatitis Clinical Pathways Using a Novel Process Mining Method. [PDF]

Healthcare (Basel), 2023
Yang X, Huang W, Zhao W, Zhou X, Shi N, Xia Q.   +5 more
europepmc   +1 more source

Supplementary Figure 1 from Higher Risk of Infections with PI3K–AKT–mTOR Pathway Inhibitors in Patients with Advanced Solid Tumors on Phase I Clinical Trials

, 2023
Saeed Rafii, Desamparados Roda, Elena Geuna, Begoña Jiménez, Karim Rihawi, Marta Capelán, Timothy A. Yap, L. Rhoda Molife, Stanley B. Kaye, Johann S. de Bono, Udai Banerji   +10 more
openalex   +1 more source

Development and Validity Testing of a Matrix to Evaluate Maturity of Clinical Pathways: A Case Study in Saskatchewan, Canada [PDF]

, 2023
Crystal Lynn Larson, Jason Vanstone, Taysa‐Rhea Mise, Susan Tupper, Gary Groot, Amir Reza Azizian   +5 more
openalex   +1 more source