A literature review on the analysis of symptom-based clinical pathways: Time for a different approach? [PDF]
Gunatilleke NJ, Fleuriot J, Anand A.
europepmc +1 more source
Effectiveness of a Clinical Pathway for Emergency Management of Pediatric Asthma [PDF]
SP Norton +3 more
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A thematic analysis of the views of neurodivergent women with a personality disorder diagnosis on clinical pathways within mental health services. [PDF]
Graham R +5 more
europepmc +1 more source
Experiences of using clinical pathways in hospitals: Perspectives of quality improvement personnel. [PDF]
Hwang JI +4 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Clinical Pathways in Knee and Hip Arthroplasty: Narrative Review on Sustainability, Quality, and Resource Management. [PDF]
Godinho M +3 more
europepmc +1 more source
Personalising clinical pathways in a London breast cancer service. [PDF]
Viney W +6 more
europepmc +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Development of data-driven clinical pathways: the big data clinical evidence-based pathways. [PDF]
Cui X +8 more
europepmc +1 more source

