Results 151 to 160 of about 2,614,061 (283)

Preliminary research of the clinical pathways of glaucomatous optic nerve damage in cases with glaucomatocyclitic crisis: A retrospective study. [PDF]

Medicine (Baltimore), 2023
Cao D, Hu J, Sun Z, Lei Q, Zhang W, Zhang Y, Zhou H.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Successful Implementation of Workflow-Embedded Clinical Pathways During the COVID 19 Pandemic. [PDF]

Qual Manag Health Care, 2023
Wendel SK, Bookman K, Holmes M, Wiler JL.   +3 more
europepmc   +1 more source

Evaluating the capacity of clinical pathways through discrete-event simulation. [PDF]

Organizing a medical facility efficiently is hard due to the numerous patient trajectories and their use of joint and scarce resources. Moreover, these trajectories tend to be complex and characterized by uncertain medical processes.
Cardoen, Brecht, Demeulemeester, Erik
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Neurorehabilitation Clinical Pathways in Stroke: The Padova Model. [PDF]

Neurol Sci
Del Felice A, Bisogno AL, Facchini S, De Pellegrin S, Baba A, Lando A, Basile AM, Piccione F, Antonini A, Maurizio C, Padova Neurorehabilitation Group.   +10 more
europepmc   +1 more source

Clinical Pathway [PDF]

, 2020
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Diagnostic Reasoning of Resident Physicians in the Age of Clinical Pathways. [PDF]

J Grad Med Educ, 2022
Congdon M, Clancy CB, Balmer DF, Anderson H, Muthu N, Bonafide CP, Rasooly IR.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source