Results 21 to 30 of about 9,826,201 (402)

Targeting inflammation to reduce cardiovascular disease risk [PDF]

, 2017
This joint themed section of the British Journal of Pharmacology and the British Journal of Clinical Pharmacology stems from a joint British Pharmacological Society – Italian Society of Pharmacology symposium held at the 37th National Congress of the ...
Cirino, Guiseppe, Maffia, Pasquale
core   +1 more source

Strong Association between Inotrope Administration and Intraventricular Hemorrhage, Gestational Age, and the Use of Fentanyl in Very Low Gestational Age Infants: A Retrospective Study

Children, 2023
This was a single center, retrospective cohort study designed to evaluate the association between the administration of inotropes to hypotensive very low gestational age infants (VLGAI) and prenatal and neonatal risk factors.
Theodora Stathopoulou, Eleni Agakidou, Christos Paschaloudis, Angeliki Kontou, Ilias Chatzioannidis, Kosmas Sarafidis   +5 more
doaj   +1 more source

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.

Human Molecular Genetics, 2005
Mutations in the WNK1 gene cause Gordon's syndrome, a rare Mendelian form of hypertension. We assessed whether common WNK1 variants might also contribute to essential hypertension (EH), a multifactorial disorder affecting > 25% of the adult population ...
S. Newhouse, C. Wallace, R. Dobson, C. Mein, J. Pembroke, M. Farrall, D. Clayton, Morris J. Brown, N. Samani, A. Dominiczak, J. Connell, J. Webster, G. Lathrop, M. Caulfield, P. Munroe, P. Munroe, Clinical Pharmacology, William Harvey   +17 more
semanticscholar   +1 more source

Clinical Pharmacology & Therapeutics: Past, Present, and Future. [PDF]

, 2017
Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline ...
Terzic, Andre, Waldman, Scott A.
core   +2 more sources

Medication Utilisation Program, Quality Improvement and Research Pharmacist—Implementation Strategies and Preliminary Findings

Pharmacy, 2021
Judicious use of medicines that considers evidence-based practice, together with cost-effectiveness, is a priority for all health care organisations. We describe an initiative to lead a Medication Utilisation Program, incorporating medication quality ...
Karen Whitfield, Ian Coombes, Charles Denaro, Peter Donovan   +3 more
doaj   +1 more source

Clinical Pharmacology and Interplay of Immune Checkpoint Agents: A Yin-Yang Balance.

Annual Review of Pharmacology and Toxicology, 2020
T cells have a central role in immune system balance. When activated, they may lead to autoimmune diseases. When too anergic, they contribute to infection spread and cancer proliferation.
A. Géraud, P. Gougis, A. Vozy, C. Anquetil, Y. Allenbach, E. Romano, E. Funck-Brentano, J. Moslehi, Douglas B. Johnson, J. Salem   +9 more
semanticscholar   +1 more source

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]

, 2012
The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco, Aldea, Ana, Alonso-Navarro, Hortensia, Bernal, María Luisa, Borobia, Alberto M., Borràs, Emma, Carballo, Miguel, Carvajal, Alfonso, García-Agúndez, José Augusto, García-Martín, Elena, García-Muñiz, José D., Gervasini, Guillermo, Jiménez-Jiménez, Félix Javier, Lucena, María Isabel, Martínez, Carmen, Sacristán, José A., Salado, Inés, Sinués, Blanca, Vicente, Jorge   +18 more
core   +4 more sources

Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant

Pharmacology Research & Perspectives, 2021
The primary aim of this study was to examine the effect of severe renal impairment (SRI) on the pharmacokinetics of lemborexant, a dual orexin receptor antagonist indicated for the treatment of insomnia.
Ishani Landry, Jagadeesh Aluri, Nancy Hall, Gleb Filippov, Satish Dayal, Margaret Moline, Larisa Reyderman   +6 more
doaj   +1 more source

Prescriptive Appropriateness: Inhospital Adherence to Proton Pump Inhibitors Deprescription Flow Chart

Pharmaceuticals, 2023
The prescriptive appropriateness of Proton Pump Inhibitors (PPIs) in polypharmacy is controversial. PPIs are often overprescribed and the risk of prescribing errors and adverse drug reactions increases for each additional drug added to therapy.
Giammarco Baiardi, Giulia Calvini, Serena Panarello, Chiara Fioravanti, Manuela Stella, Antonietta Martelli, Giancarlo Antonucci, Francesca Mattioli   +7 more
doaj   +1 more source

Traditional Chinese Medicine and Clinical Pharmacology

Drug Discovery and Evaluation: Methods in Clinical Pharmacology, 2020
Traditional Chinese Medicine (TCM) represents thousands of years in treatment protocols for health, healing, and longevity and has evolved into a complex healthcare system.
A. Marshall
semanticscholar   +1 more source