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Statistical significance and clinical significance [PDF]
Medicine is evolving faster than ever and the web and communication channels, among other technological improvements, facilitate the capacity for knowledge generation and knowledge diffusion, not only in the field of medicine but also for science in general. The form of knowledge diffusion that is used most is the publication of scientific articles. In
Alessandro Wasum Mariani +1 more
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Knowledge and Attitude Towards the Translation of Medical Research to Clinical Benefit Amongst Researchers in A Tertiary Care Hospital [PDF]
Introduction: One of the primary goals of any biomedical researcher should be practical applicability or the translation of scientific discoveries to clinical care.
S Shanmugapriya +2 more
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Current controversies: Null hypothesis significance testing
Traditional null hypothesis significance testing (NHST) incorporating the critical level of significance of 0.05 has become the cornerstone of decision‐making in health care, and nowhere less so than in obstetric and gynecological research. However, such
Philip M. Sedgwick +3 more
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It is incredibly essential that the current clinicians and researchers remain updated with findings of current biomedical literature for evidence-based medicine.
Hunny Sharma
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The tyranny of the P-value: effect size matters
Statistical significance does not necessarily imply clinical significance. A P-value of less than 0.05 does not guarantee that the result will be important. Effect size needs to be calculated in order to appraise clinical relevance.
Leslie Citrome
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An analysis of the variations and clinical applications of the lateral circumflex femoral artery
BACKGROUND: Identifying the arterial variation of the lateral circumflex femoral artery (LCFA) is a vital step in planning surgical and radiological approach.
M. Ma +8 more
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Clinical significance of Streptococcus members in developing periodontitis
Bacteria of the genus Streptococcus are one of the most numerous and diverse representatives in the normal biocenosis of human organs and systems particularly being abundant as obligatory inhabitants of the oral cavity.
I. V. Bazhutova +5 more
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CARD9 as a potential therapeutic target in lung cancer
Caspase recruitment domain-containing protein 9 (CARD9) is highly expressed in myeloid cells and has been identified as a central regulator of innate immunity.
Ruanmei Sheng, Zhiwen Yang
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The function and clinical implication of circular RNAs in lung cancer
Lung cancer is the leading cause of cancer-related deaths worldwide. Despite the recent advent of promising new targeted therapies, lung cancer diagnostic strategies still have difficulty in identifying the disease at an early stage.
Wenjun Ren +5 more
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Interpreting "statistical hypothesis testing" results in clinical research
Difference between "Clinical Significance and Statistical Significance" should be kept in mind while interpreting "statistical hypothesis testing" results in clinical research.
Sanjeev B Sarmukaddam
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