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Psychiatry and Behavioral Sciences, 2014
Statistical significance (p value) is a considerable measure when the manuscripts were reading or interpreting. On the other hand clinical importance, which is important at least as statistical significance, may not consider every time by authors or ...
Selim Kılıc
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Targeting FBPase is an emerging novel approach for cancer therapy

Cancer Cell International, 2018
Cancer is a leading cause of death in both developed and developing countries. Metabolic reprogramming is an emerging hallmark of cancer. Glucose homeostasis is reciprocally controlled by the catabolic glycolysis and anabolic gluconeogenesis pathways ...
Gao-Min Liu, Yao-Ming Zhang
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RETRACTED: The value, diagnostic efficacy and clinical significance of functional magnetic resonance imaging in evaluating the efficacy of neoadjuvant chemotherapy in patients with triple negative breast cancer

Frontiers in Oncology, 2023
BackgroundBreast cancer (BC) is a common malignant tumor in female. In recent years, with the change of fertility pattern and lifestyle, the incidence of breast cancer is increasing year by year, seriously endangering the health and life of women. MRI is
Xiaoping He, Zongsheng Wang, Ying Zhou, Yongli Feng   +3 more
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Interpreting P Values in 2023

Journal of Patient-Centered Research and Reviews, 2023
If recent experiences shared among the biostatistician community are indicative of a sea change in research, then a most-welcome culture shift in dialogue surrounding the proper use and interpretation of the P value, which measures statistical ...
Jennifer K. Homa-Bonell
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Clinical significance and role of coinfections with respiratory pathogens among individuals with confirmed severe acute respiratory syndrome coronavirus-2 infection

Frontiers in Public Health, 2022
IntroductionThis study aimed to determine the prevalence, viral profile, and clinical features of coinfections with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and other respiratory viruses.MethodsNasopharyngeal samples and clinical data
Ivelina Trifonova, Iva Christova, Iveta Madzharova, Svetla Angelova, Silvya Voleva, Ralitsa Yordanova, Tatiana Tcherveniakova, Stefka Krumova, Neli Korsun   +8 more
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The Clinical Significance and Mechanisms of REG4 in Human Cancers

Frontiers in Oncology, 2021
Regenerating islet-derived type 4 (REG4), a member of the calcium-dependent lectin gene superfamily, is abnormally expressed in various cancers, such as colorectal, gastric, gallbladder, pancreatic, ovarian, prostate, and lung cancer.
Junyan Zhang, Zhi Zhu, Zhifeng Miao, Xuanzhang Huang, Zhe Sun, Huimian Xu, Zhenning Wang   +6 more
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Determinants of Diabetic Peripheral Neuropathy and Their Clinical Significance: A Retrospective Cohort Study

Frontiers in Endocrinology, 2022
BackgroundIn this study, we investigated the epidemiological characteristics and predictors of diabetic peripheral neuropathy (DPN) in adult patients with type 2 diabetes mellitus (DM).MethodsThe study was designed as a retrospective cohort trial at the ...
Yifan Cheng, Wen Cao, Junzhe Zhang, Jiabin Wang, Xiang Liu, Qianqian Wu, Qingxia Lin   +6 more
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FAM60A promotes osteosarcoma development and progression

Cancer Medicine, 2023
Background Osteosarcoma (OS) is a highly malignant primary bone tumor. Family of homology 60A (FAM60A) reportedly contributes to the malignant growth of some tumors.
Yu Sun, Yu‐Nan Man, Jin‐hui Cheng, Jing‐tang Li, Ya‐yun Liu   +4 more
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Expression and clinical significance of NCOA5 in epithelial ovarian cancer

Frontiers in Oncology, 2023
BackgroundNuclear receptor coactivator 5 (NCOA5) plays a significant role in the progression of human cancer. However, its expression in epithelial ovarian cancer (EOC) is unknown.
Xiaoping Song, Da Qian, Ping Dai, Qian Li, Qiuping Xi, Kailv Sun   +5 more
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What is a biomarker?: From its discovery to clinical application [PDF]

Journal of Medical Biochemistry, 2011
The term biomarker in medicine most often stands for a protein measured in the circulation (blood) whose concentration indicates a normal or a pathological response of the organism, as well as a pharmacological response to the applied therapy.
Majkić-Singh Nada
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