Results 231 to 240 of about 2,866,404 (318)

Landscape of circular RNAs in acute myeloid leukemia and their clinical significance. [PDF]

NPJ Precis Oncol
Nguyen TH, Nguyen MH, Nguyen HN, Erkers T, Östling P, Bohlin A, Österroos A, Jafari R, Orre LM, Lehtiö J, Lehmann S, Kallioniemi O, Pawitan Y, Vu TN.   +13 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer. [PDF]

Clin Transl Allergy
Alder J, Lacy KE, Josephs DH, Spicer J, Bax HJ, Karagiannis SN, Chauhan J.   +6 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Correction: Expression and clinical significance of plasma microRNA-155 in patients with primary Sjögren's disease. [PDF]

BMC Immunol
Liu Q, Zhao Y, Zhao H, Xu C, Guo H.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The mechanisms of regulatory T cells in the immune microenvironment of multiple myeloma and clinical significance. [PDF]

Front Immunol
Du L, Jiang Y, Zhou Q, Xu F.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Immune-mediated multisystem injury associated with monoclonal gammopathy of clinical significance: a case report. [PDF]

Front Immunol
Jin X, Duan X, Zhang R, Sun Y, Qian M, Li X, Ma D, Li X, Zhang X, Shen M, Zeng X, Xu N, Zhuang J.   +12 more
europepmc   +1 more source