Results 31 to 40 of about 10,048,421 (237)

Clinical comparative study of optimized metronidazole loaded lipid nanocarrier vaginal emulgel for management of bacterial vaginosis and its recurrence

Drug Delivery, 2021
The main focus of the current work was to design, evaluate and clinically compare the efficiency of novel metronidazole (MTD) loaded solid lipid nanoparticles (SLNs) vaginal emulgel with the marketed vaginal gel (Metron®) against Bacterial vaginosis (BV).
Noha M. Badawi, Mona A. Elkafrawy, Rania M. Yehia, Dalia A. Attia   +3 more
doaj   +1 more source

Painful Diabetic Neuropathy: Sex-Specific Mechanisms and Differences from Animal Models to Clinical Outcomes

Cells
Diabetes is a chronic and progressive disease associated with high blood glucose levels. Several co-morbidities arise from diabetes, the most common and severe one is diabetic neuropathy whose symptoms also include pain hypersensitivity. Currently, there
Emma Merlin, Chiara Salio, Francesco Ferrini   +2 more
doaj   +1 more source

Electronic health records to facilitate clinical research [PDF]

, 2016
Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome
Blomster, Juuso I., Cowie, Martin R., Curtis, Lesley H., Duclaux, Sylvie, Ford, Ian, Fritz, Fleur, Goldman, Samantha, Janmohamed, Salim, Kreuzer, Jörg, Leenay, Mark, Michel, Alexander, Ong, Seleen, Pell, Jill P., Southworth, Mary Ross, Stough, Wendy Gattis, Thoenes, Martin, Zalewski, Andrew, Zannad, Faiez   +17 more
core   +2 more sources

The role of weaning in brace treatment for developmental dysplasia of the hip: time to define best practice?

Bone & Joint Open
Aims: In infants aged under six months with developmental dysplasia of the hip (DDH), the use of a removable brace is considered the gold-standard treatment. However, considerable variation exists for brace removal after ‘successful’ treatment.
Joanna Craven, Ioan Davies, Daniel C Perry   +2 more
doaj   +1 more source

Anti-inflammatory Effects of Olive Oil and Its Components. Prospects of Application in the Treatment of Inflammatory Bowel Diseases

Педиатрическая фармакология
In recent years, there has been a significant increase in the prevalence of inflammatory bowel diseases. Despite the significant progress made in the instrumental diagnosis of this group of diseases, their treatment in most cases remains formalized ...
Anatoly I. Khavkin, Andrew V. Nalyotov, Maria A. Matsynina   +2 more
doaj   +1 more source

Animal mesenchymal stem cell research in cartilage regenerative medicine – a review

Veterinary Quarterly, 2019
Healing of articular cartilage is a major clinical challenge as it also lacks a direct vasculature and nerves, and carries a limited number of resident chondrocytes that do not proliferate easily.
Mudasir Bashir Gugjoo, Amarpal, Mujeeb-Ur Rehman Fazili, Mohmmad Abrar Gayas, Raja Aijaz Ahmad, Kuldeep Dhama   +5 more
doaj   +1 more source

Metabolic therapy in cardiology from the perspective of evidence-based medicine

Фундаментальная и клиническая медицина, 2021
Over the past few decades, various applications of the metabolic drugs have been extensively tested. Most of them affect oxygen-dependent processes, improving cellular metabolism and increasing tissue resistance to hypoxia and ischemia.
V. I. Kostin, O. A. Shangina, V. G. Shelikhov   +2 more
doaj   +1 more source

Performance of mesenchymal cell-scaffold constructs in human oral reconstructive surgery: a systematic review [PDF]

, 2016
Background: Different sources of cultured cells combined with different scaffolds (allogenic, xenogeneic, alloplastic or composite materials) have been tested extensively in vitro and in preclinical animal studies, but there have been only a few ...
ANNIBALI, Susanna, Cristalli, Maria Paola, LA MONACA, Gerardo, MARINI, ROBERTA, Patini, Romeo, PRANNO, NICOLA   +5 more
core   +1 more source

Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]

, 2012
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat, AM Cheung, C Brun-Buisson, C Rossi, Cecilia M O’Kane, Christine McNally, Daniel F McAuley, DJ Kor, Excellence NIfHaC, F Gao Smith, Gavin D Perkins, GD Rubenfeld, GR Bernard, Grainne Crealey, Irish Critical Care Trials Group, John G Laffey, KF Schulz, LA Curtis, Lynn Murphy, M Shyamsundar, MA Matthay, Mark Cross, Michael Stevenson, MS Herridge, RG Brower, S Harvey, SE Erickson, T Craig, The ARDS Network investigators, The EuroQol Group, TR Craig, TW Felton   +31 more
core   +1 more source

Studies on the clinical significance of nonesterified and total cholesterol in urine [PDF]

, 1981
Gas-liquid chromatographic determinations of nonesterified and total urinary cholesterol were performed in 137 normals, 264 patients with various internal diseases without evidence of neoplasias or diseases of the kidney or urinary tract, 497 patients ...
A. Pickel, A. Stadler, BA Vela, D Jüngst, D Jüngst, D. Jüngst, DE Comings, E Bloch, F. J. Marsx, H Sobotka, H Sobotka, H. J. Karl, HF Acevedo, HF Acevedo, HF Acevedo, HF Acevedo, HF Acevedo, HF Acevedo, J Bing, J Frick, J. Wallner, JA Belis, JC Sutherland, JG Zimmer, JW Eagen, M Bruger, M Bruger, M Spiteller-Friedmann, MM Burchell, MM Burchell, P Kerkhoven, S Klahr, SG Mendoza de, TM Chu, W Trappe, W. Eiermann   +35 more
core   +2 more sources