Results 91 to 100 of about 1,991,569 (312)

Open-Label Randomized Clinical Trial of Atropine Bolus Injection Versus Incremental Boluses Plus Infusion for Organophosphate Poisoning in Bangladesh [PDF]

open access: bronze, 2012
Mohammed Joynal Abedin   +5 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Recent landscape and trends for industry‐sponsored pediatric clinical trials in China from 2013 to 2022

open access: yesPediatric Investigation
Importance Pediatric medication is a challenging issue globally. Promoting trials of medications for children and implementing measures to encourage innovation for addressing unmet medical and health needs are important.
Chang Liu   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Toward a Generalized Framework of Core Measurement Areas in Clinical Trials: A Position Paper for OMERACT 11 [PDF]

open access: bronze, 2014
Maarten Boers   +9 more
openalex   +1 more source

Randomised clinical trial: minesapride vs placebo for irritable bowel syndrome with predominant constipation [PDF]

open access: bronze, 2020
Tatsuto Hamatani   +5 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme [PDF]

open access: gold, 2017
Hisashi Yamanaka   +19 more
openalex   +1 more source

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