Results 211 to 220 of about 14,066,519 (402)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

A Review of Clinical Trials in Down Syndrome. [PDF]

Int Rev Res Dev Disabil
Denne E, Channell MM, White N, Fidler D, Baumer N, Wu J, Tapia IE, Froehlich T, Hartley S, Esbensen AJ.   +9 more
europepmc   +1 more source

Foundation clinical trials [PDF]

Breast Cancer Research, 2009
openaire   +3 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Blockchain integration for rare disease clinical trials. [PDF]

Ann Med Surg (Lond)
Riaz U, Talha M, Ali U, Hassan M, Mahato RK.   +4 more
europepmc   +1 more source

UK-Cuboid Randomized Complete Block Design: A Complete Three Way Layout for Large Multi-Center Clinical Trials

, 2017
N. Uthayakumaran, M Das, N Giri, Vishwanth Reddy, S, N Uthayakumaran, N Uthayakumaran, N Uthayakumaran, N Uthayakumaran, N Uthayakumaran   +9 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Decentralized Clinical Trials in Pediatrics: Is Italy Ready? [PDF]

J Clin Med
Paternuosto G, Flamigni A, Zanier M, Bonifacio B, Schillani G, Cirino M, Krcalic S, Tommasi S, Tizi F, Arbo A, Zanon D, Maestro A.   +11 more
europepmc   +1 more source

The Effectiveness of Virtual-Real Fusion Teaching Models in Clinical Skills Training: A Randomized -Controlled Trial Comparing Touch Surgery and Traditional Teaching Aids for Thoracentesis [PDF]

Chengming Ding, Haonan Zhang, Heng Yang, Jia Yang, Shiyu Zhou, Zhengwen Lei   +5 more
openalex   +1 more source

G-CSF and G-CSF biosimilars: a meta-analysis of randomized clinical trials in breast cancer patients [PDF]

, 2017
Edoardo Botteri, Andriy Krendyukov, Giuseppe Curigliano   +2 more
openalex   +1 more source