Results 51 to 60 of about 7,990,092 (312)

Clinical Trials Unit Newsletter - Issue 01 [PDF]

What\u27s inside this issue: AKU receives JCIA reaccreditation - Clinical Trials Unit rejoice Director’s Message Informative Snippets AKU Site Surpasses Target Sample Size in the D-LIVR Global Trial Clinical Trials Unit celebrates World Pharmacists Day ...
Clinical Trials Unit (CTU),
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Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Rapid qualitative analysis of recruitment obstacles in the FORVAD (Posterior Cervical Foraminotomy surgery versus Anterior Cervical Discectomy surgery in the treatment of cervical brachialgia) randomised, controlled trial

Trials
Background The number of surgical trials is increasing but such trials can be complex to deliver and pose specific challenges. A multi-centre, Phase III, RCT comparing Posterior Cervical Foraminotomy versus Anterior Cervical Discectomy and Fusion in the ...
Rebecca Talbot, Ruchi Higham, Julie Croft, Gemma Ainsworth, Sarah Brown, Rachel Kelly, Deborah Stocken, Simon Thomson, Nikki Rousseau   +8 more
doaj   +1 more source

Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study. [PDF]

, 2006
National Coordinating Centre for Research Methodology; Medical Research Council, UK Department of Health; Chief Scientist OfficeNot peer reviewedPublisher ...
Snowdon, Claire, Grant, Adrian M, Garcia, J, Francis, D, Francis, David, McDonald, Alison Mary, Knight, R.C, Elbourne, Diana, Knight, Rosemary, Elbourne, Diana R., McDonald, A.M, Grant, Adrian, Garcia Jo, Roberts Ian, McDonald Alison M, Elbourne, Diana R, Francis, David; id_orcid, Grant, Adrian Maxwell, McDonald, Alison M, Campbell Marion K, Entwistle, Vikki A, Snowdon, C, Campbell, Marion K, Campbell, M.K, Snowdon Claire, Entwistle, V.A, Campbell, Marion K., Francis David, Entwistle, Vicky, MacDonald, Alison M., McDonald, Alison, Grant, Adrian M., Grant Adrian M, Knight, Rosemary C, Knight, Rosemary C., Entwistle Vikki A, Roberts, Ian, Garcia, Jo, Grant, A.M, Campbell, Marion, Knight Rosemary C, Elbourne Diana R, Entwistle, Vikki A., Elbourne, D.R, Entwistle, Vikki, Campbell, Marion Kay, Roberts, I   +46 more
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Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Research Report 2008–2009 [PDF]

, 2010
The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, takes part in trials of national and international collaborative trial groups and contributes expertise to trials run by others ...
NHMRC Clinical Trials Centre
core  

Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility [PDF]

, 2013
Seamless phase II/III clinical trials combine traditional phases II and III into a single trial that is conducted in two stages, with stage 1 used to answer phase II objectives such as treatment selection and stage 2 used for the confirmatory analysis ...
Todd, Susan C., Susan Todd, Todd, Susan, Peter K. Kimani, Stallard, Nigel, Nigel Stallard, Kimani, Peter K.   +6 more
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Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Initial experience of a digital training resource for modified Rankin scale assessment in clinical trials [PDF]

, 2007
<p><b>Background and Purpose:</b> The modified Rankin Scale (mRS) is the preferred measure of disability in cerebrovascular clinical trials, but its value is restricted by interobserver variability.
Lees, K.R., Walters, M.R., Dawson, J., Quinn, T.J., Hardemark, H.G.   +4 more
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Developing a knowledge transfer and exchange strategy for a clinical trials unit

Trials
Need for a strategic approach to knowledge transfer and exchange Late-phase clinical trials and systematic reviews find results that have the potential to improve health outcomes for people.
Annabelle South, Berta Terré Torras, Hannah Rush, Anna Goodman, Sharon Love   +4 more
doaj   +1 more source