Results 41 to 50 of about 2,286,280 (167)

Ethical Problems in Clinical Trials [PDF]

, 1986
Schaffner introduces four articles on clinical trials (by F. Gifford, J.B. Kadane, L. Kopelman, and D. Marquis) by providing an historical and methodological context within which to interpret them.
Schaffner, Kenneth F.
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Clinical Trials: Two Neglected Ethical Issues [PDF]

, 1993
Ethical reasons are presented for requiring 1) that a proposal for a clinical trial should be accompanied by a thorough review of all previous trials that have examined the same and closely related questions, and 2) that a trial should be approved by a ...
Herxheimer, Andrew
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Clinical Trials Unit Newsletter - Issue 01 [PDF]

What\u27s inside this issue: AKU receives JCIA reaccreditation - Clinical Trials Unit rejoice Director’s Message Informative Snippets AKU Site Surpasses Target Sample Size in the D-LIVR Global Trial Clinical Trials Unit celebrates World Pharmacists Day ...
Clinical Trials Unit (CTU),
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American College of Rheumatology/European League Against Rheumatism Provisional Definition of Remission in Rheumatoid Arthritis for Clinical Trials [PDF]

, 2011
Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there is no widely used definition of remission that is stringent but achievable and could be applied uniformly as an outcome measure in clinical trials.
Matucci-Cerinic, M., Richards, P., American College of Rheumatology,, Robert Landewé, Pamela Richards, Alan Tyndall, Wit, M. de, Siegel, Jeffrey N., John Kirwan, Gillian Hawker, Daniel Aletaha, Simon, L.S., Dougados, Maxime, White, Barbara, Montie, Pamela, Kvien, T.K., Andrew Brown, Funovits, J., Combe, Bernard, Aletaha, Daniel, Tuyl, H.D. van, Tuulikki Sokka, Brooks, Peter, Brown, Andrew, Kirwan, J, Josef S. Smolen, Bathon, J., Suzan Verstappen, Choi, Hyon, Allaart, Cornelia F, Furst, Daniel E., Kaleb Michaud, Heijde, D. van der, van der Heijde, D., George Wells, Cornelia F Allaart, Furst, D., Landewe, R., Josef S Smolen, Brooks, Peter M., Allaart, Cornelia F., Sokka, Tuulikki, Maarten de Wit, David T. Felson, Peter Brooks, Verstappen, Suzan, Boers, M., Choi, H., Khanna, Dinesh, Khanna, D., Aletaha, D., Strand, Vibeke, Bombardieri, Stefano, Kvien, Tore K., Wolfe, F, Boers, Maarten, Stefano Bombardieri, Listing, J., Tugwell, P, Zhang, B., Joan Bathon, Lee S. Simon, Barbara White, Richards, Pamela, Wolfe, Frederick, Sokka, T., Maxime Dougados, Angela Zink, van Tuyl, Lilian H. D., van Tuyl, H.D., Hawker, G., Brown, A., Felson, David T., Paul Emery, Keystone, E., Bathon, Joan, Listing, Joachim, Verstappen, S., Zink, Angela, Combe, B., Michaud, K., Hyon Choi, Wolfe, F., Daniel Furst, Joachim Listing, Funovits, Julia, Gomez-Reino, J., de Wit, Maarten P. T., Emery, Paul, Gomez-Reino, Juan, Wells, George, Jeffrey N Siegel, Lilian H D van Tuyl, Theodore Pincus, Zink, A., Michaud, Kaleb, Marco Matucci-Cerinic, Tyndall, A., Lee S Simon, Keystone, Edward, European League Against Rheumatism,, Landewé, Robert, Emery, P., Julia Funovits, Zhang, Bi, Jeffrey N. Siegel, Maarten Boers, Van Tuyl, Lilian H D, de Wit, Maarten, Pincus, T., Hawker, Gillian, Strand, V., Edward Keystone, Frederick Wolfe, Martin-Mola, E., Pamela Montie, de Wit, M., van Tuyl, L.H.D., Tore K. Kvien, Cornelia F. Allaart, Emilio Martin-Mola, Matucci-Cerinic, Marco, Emery, P, Zhang, Bin, Tyndall, Alan, Bernard Combe, Dougados, M., Kirwan, J., David T Felson, Tugwell, Peter, Allaart, C.F., Brown, A, Juan Gomez-Reino, Vibeke Strand, Tuyl, L.H.D. van, Montie, P., Brooks, P., Peter Tugwell, Kirwan, John, Simon, Lee S., Furst, Daniel, Bombardieri, S., van der Heijde, Desirée, Dinesh Khanna, White, B., Pincus, Theodore, Wells, G., Siegel, J.N., Martin-Mola, Emilio, Tugwell, P., Felson, D.T., Desirée van der Heijde, Smolen, Josef S., Lilian H. D. van Tuyl, Smolen, J.S., Strand, V, Bin Zhang   +156 more
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A cross-sectional survey on the early impact of COVID-19 on the uptake of decentralised trial methods in the conduct of clinical trials [PDF]

, 2022
BACKGROUND: The COVID-19 pandemic significantly impacted the conduct of clinical trials through delay, interruption or cancellation. Decentralised methods in clinical trials could help to continue trials during a pandemic. This paper presents the results
Trials@Home Consortium
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Improving the external validity of clinical trials: the case of multiple chronic conditions [PDF]

, 2013
The U.S. Department of Health and Human Services vision and strategic framework on multiple chronic conditions (MCCs) incorporates recommendations designed to facilitate research that will improve our knowledge about interventions and systems that will ...
Fortin Martin MD, MSc, CFPC, Susan Smith, Martin Fortin, Martin Fortin (3405860), Fortin, Martin, Smith, Susan M., Smith M. Susan, Susan Smith (7896224)   +7 more
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Experience and Challenges from Clinical Trials with Malaria Vaccines in Africa. [PDF]

, 2013
Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades ...
Mpina, Maxmillian, Abdulla, Salim, Shekalaghe, Seif, Tanner, M., Salim Abdulla, Mpina, M., Seif Shekalaghe, Shekalaghe, S., Marcel Tanner, Salim, N., Kafuruki, Shubis, Mzee, T., Tutu Mzee, Abdulla, S., Grace Mwangoka, Mwangoka, G., Tanner, Marcel, Beverly Msambichaka, Mzee, Tutu, Ogutu, Bernhards, Mwangoka, Grace, Nahya Salim, Msambichaka, Beverly, Salim, Nahya, Shubis Kafuruki, Ogutu, B., Kafuruki, S., Bernhards Ogutu, Maxmillian Mpina, Msambichaka, B.   +29 more
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Trials, Tricks and Transparency: How Disclosure Rules Affect Clinical Knowledge [PDF]

Scandals of selective reporting of clinical trial results by pharmaceutical firms have underlined the need for more transparency in clinical trials. We provide a theoretical framework which reproduces incentives for selective reporting and yields three ...
Nicolás Porteiro, Paula González, Matthias Dahm   +2 more
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The Continuing Unethical Conduct of Underpowered Clinical Trials [PDF]

, 2002
Despite long-standing critiques of the conduct of underpowered clinical trials, the practice not only remains widespread, but also has garnered increasing support. Patients and healthy volunteers continue to participate in research that may be of limited
Halpern, Scott D., Berlin, Jesse A., Karlawish, Jason H.T.   +2 more
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Ethics review of decentralized clinical trials (DCTs): Results of a mock ethics review. [PDF]

, 2022
Decentralized clinical trials (DCTs) can be a valuable addition to the clinical trial landscape. However, the practice of DCTs is dependent on a regulatory system designed for conventional (site-based) trials.
Trials@Home Consortium
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