Results 21 to 30 of about 3,552,558 (305)

The COV-ED Survey: exploring the impact of learning and teaching from home on parent/carers’ and teachers’ mental health and wellbeing during COVID-19 lockdown

BMC Public Health, 2022
Background Following the emergence of COVID-19 in the UK, on March 18th 2020 the majority of schools in England closed and families and teachers were tasked with providing educational support for children and adolescents within the home environment ...
C Connor, N De Valliere, J Warwick, S Stewart-Brown, A Thompson   +4 more
doaj   +1 more source

Translational perspectives on perfusion-diffusion mismatch in ischemic stroke [PDF]

, 2013
Magnetic resonance imaging has tremendous potential to illuminate ischemic stroke pathophysiology and guide rational treatment decisions. Clinical applications to date have been largely limited to trials.
Campbell, Bruce C. V., Macrae, I. Mhairi
core   +1 more source

Criteria for the use of omics-based predictors in clinical trials. [PDF]

, 2013
The US National Cancer Institute (NCI), in collaboration with scientists representing multiple areas of expertise relevant to 'omics'-based test development, has developed a checklist of criteria that can be used to determine the readiness of omics-based
A Dupuy, AM Molinaro, B Freidlin, Barbara A. Conley, David A. Eberhard, Deborah J. Shuman, HM Moore, J Subramanian, James H. Doroshow, James V. Tricoli, Jeremy M. G. Taylor, Jill P. Mesirov, JT Leek, Kelly Y. Kim, KK Dobbin, L Shi, Lisa M. McShane, LM McShane, Margaret M. Cavenagh, Mei-Yin C. Polley, P. Mickey Williams, R Simon, Richard M. Simon, RM Simon, Tracy G. Lively, William L. Bigbee   +25 more
core   +2 more sources

Monitoring performance of sites within multicentre randomised trials: a systematic review of performance metrics

Trials, 2018
Background Large multicentre trials are complex and expensive projects. A key factor for their successful planning and delivery is how well sites meet their targets in recruiting and retaining participants, and in collecting high-quality, complete data ...
Kate F. Walker, Julie Turzanski, Diane Whitham, Alan Montgomery, Lelia Duley   +4 more
doaj   +1 more source

Active Clinical Trials for Personalized Medicine

, 2015
Individualized treatment rules (ITRs) tailor treatments according to individual patient characteristics. They can significantly improve patient care and are thus becoming increasingly popular.
Cheng, Guang, Minsker, Stanislav, Zhao, Ying-Qi   +2 more
core   +2 more sources

Stem cell clinical trials [PDF]

, 2013
No description ...
Rosemann, Achim
core  

Lewy Body Dementia Association\u27s Research Centers of Excellence Program: Inaugural Meeting Proceedings. [PDF]

, 2019
The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator\u27s meeting was held on December 14, 2017, in New Orleans.
Amodeo, Katherine, Armstrong, Melissa, Barrett, Matt, Boeve, Brad, Christie, Tina, Domoto-Reilly, Kimiko, Duda, John, Galasko, Douglas, Galvin, James E., Goldman, Jennifer, Gomperts, Stephen, Graff-Radford, Neill, Graham, Todd, Holden, Samantha, Honig, Lawrence, Huddleston, Daniel, Irwin, David, Kaufer, Daniel, Koehler, Mike, Leverenz, James, Lippa, Carol, Litvan, Irene, Lunde, Angela, Manning, Carol, Marder, Karen, McKeith, Ian G., Moussa, Charbel, Onyike, Chiadi, Pagan, Fernando, Pantelyat, Alexander, Paulson, Henry, Pelak, Victoria, Peterson, Bethany, Poston, Kathleen, Quinn, Joseph, Richard, Irene, Richards, Ian, Rosenthal, Liana S., Sabbagh, Marwan, Scharre, Douglas, Sha, Sharon, Shill, Holly, Siderowf, Andrew, Taylor, Angela, Torres-Yaghi, Yasar   +44 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

A phase I/II randomized controlled clinical trial to assess the feasibility, safety, and preliminary effectiveness of paracetamol in resolving acute kidney injury in children with severe malaria

Trials
Background Acute kidney injury (AKI) is prevalent among children with severe malaria, contributing to considerable morbidity and mortality. Oxidative stress has been implicated in the pathophysiology of malaria-induced AKI, and paracetamol, with its ...
George Paasi, Cate Namayanja, Paul Ongodia, Charles Benard Okalebo, William Okiror, Grace Abongo, George Masifa, Denis Amorut, Rita Muhindo, Peter Olupot-Olupot, the PARIST trial study group   +10 more
doaj   +1 more source

Advancing Pediatric Antibacterial Drug Development: A Critical Need to Reinvent our Approach. [PDF]

, 2019
The Clinical Trials Transformation Initiative convened with several groups in the pediatric antibacterial drug development community with the goal of identifying challenges and recommending ways to improve current practice.
Bradley, John, Clinical Trials Transformation Initiative’s Pediatric Antibiotic Drug Development Program, Nambiar, Sumathi, Noel, Gary J   +3 more
core   +1 more source