Results 11 to 20 of about 2,286,280 (167)

Managing clinical trials. [PDF]

open access: yes, 2010
Managing clinical trials, of whatever size and complexity, requires efficient trial management. Trials fail because tried and tested systems handed down through apprenticeships have not been documented, evaluated or published to guide new trialists ...
Barbara Farrell   +11 more
core   +1 more source

What can we learn from clinical trials of anticonvulsant drugs in epilepsy? [PDF]

open access: yes, 2002
Any physician who intends to utilize the available antiepileptic drugs (AEDs) judiciously, cannot do so without being well versed on their pharmacological properties and the large body of evidence that is continuously accumulating on their relative ...
What Can We Learn From Clinical Trials Of Anticonvulsant Drugs In Epilepsy?   +1 more
core   +1 more source

What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. [PDF]

open access: yes, 2006
National Coordinating Centre for Research Methodology; Medical Research Council, UK Department of Health; Chief Scientist OfficeNot peer reviewedPublisher ...
McDonald, AM   +70 more
core   +1 more source

Marketing and clinical trials : a case study [PDF]

open access: yes, 2007
Background: Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well ...
Francis, D   +54 more
core   +1 more source

Communication about children's clinical trials as observed and experienced: qualitative study of parents and practitioners. [PDF]

open access: yes, 2011
Recruiting children to clinical trials is perceived to be challenging. To identify ways to optimise recruitment and its conduct, we compared how parents and practitioners described their experiences of recruitment to clinical ...
Shilling, V   +30 more
core   +1 more source

Pharmacokinetic research in children: an analysis of registered records of clinical trials. [PDF]

open access: yes, 2011
BACKGROUND: Reported off-label/unlicensed prescribing rates in children range from 11% to 80%. Research into pharmacokinetic profiles of children's medicines is essential in the creation of more knowledge on the safety and efficacy of medicines in ...
Rademaker, Carin MA   +5 more
core   +1 more source

Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]

open access: yes, 2009
Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Raftery James   +7 more
core   +1 more source

Assessment of outcome in clinical trials in mild Alzheimer 19s disease: urgent time for a rethink? [PDF]

open access: yes, 2013
Introduction: A major barrier for clinical trials in Alzheimer's disease is the lack of sensitive clinical endpoints for the early stages. Until recently, regulatory agencies have required demonstration of improvement in two disease domains, cognition ...
McGoldrick, S.   +12 more
core  

Sharing data from clinical trials: the rationale for a controlled access approach. [PDF]

open access: yes, 2015
The move towards increased transparency around clinical trials is welcome. Much focus has been on under-reporting of trials and access to individual patient data to allow independent verification of findings.
Parmar, MK   +11 more
core   +1 more source

Personal benefit, or benefiting others? Deciding whether to take part in clinical trials [PDF]

open access: yes, 2010
Background: Participation in clinical trials is critical for the success of evidence-based healthcare. Much previous research suggests that people take part in clinical trials mostly for altruistic reasons, and that deriving personal benefit is a ...
Locock, Margaret   +6 more
core   +1 more source

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