Results 101 to 110 of about 1,662,530 (262)
(n-3) Fatty Acids: Clinical Trials in People with Type 2 Diabetes.
Advances in Nutrition, 2010 Recent human clinical trials of the effects of (n-3) fatty acids on participants with type 2 diabetes (T2D) were reviewed, focusing on 11 clinical trials conducted within the past 4 y, and subsequent to a Cochrane Database meta-analysis of this topic ...
S. Hendrich
semanticscholar +1 more source
SY30-1 Topics on basic and translational breast cancer research of early phase clinical trial
, 2022 Takahiro Kogawa
openalex +1 more source
Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing
Revista de Gastroenterología de México (English Edition), 2019 Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy. There were 26 patients in each group. Group A received topical diltiazem in the anal region three times a day. Group B
Ulises Rodríguez-Wong +2 more
openaire +4 more sources
Cell therapy of periodontium: from animal to human?
Frontiers in Physiology, 2013 Periodontitis is a chronic inflammatory disease affecting the soft and hard tissues supporting the teeth, which often leads to tooth loss. Its significant impact on the patient’s general health and quality of life point to a need for more effective ...
Elena Andreea eTrofin +3 more
doaj +1 more source
A global rank end point for clinical trials in acute heart failure.
Circulation: Heart Failure, 2010 Hospitalization for acute heart failure (AHF) is a major public health problem, with >1 million hospitalizations annually in the United States.1 The development of new therapies for patients with AHF remains a significant challenge.2 One aspect of ...
G. Felker, A. Maisel
semanticscholar +1 more source
Comparing Biomarkers as Trial Level General Surrogates [PDF]
arXiv, 2015 An intermediate response measure that accurately predicts efficacy in a new setting can reduce trial cost and time to product licensure. In this paper, we define a trial level general surrogate as a trial level intermediate response that accurately predicts trial level clinical responses.
arxiv
Frontiers in Oncology, 2015 Introduction: The burden of cervical cancer is large and growing in developing countries, due in large part to limited access to screening services and lack of human papillomavirus (HPV) vaccination.
Gita eSuneja +5 more
doaj +1 more source
Exploring the Generalization of Cancer Clinical Trial Eligibility Classifiers Across Diseases [PDF]
arXivClinical trials are pivotal in medical research, and NLP can enhance their success, with application in recruitment. This study aims to evaluate the generalizability of eligibility classification across a broad spectrum of clinical trials. Starting with phase 3 cancer trials, annotated with seven eligibility exclusions, then to determine how well ...
arxiv
Retrieval-Reasoning Large Language Model-based Synthetic Clinical Trial Generation [PDF]
arXivMachine learning (ML) exhibits promise in the clinical domain. However, it is constrained by data scarcity and ethical considerations, as the generation of clinical trials presents significant challenges due to stringent privacy regulations, high costs, and the extended duration required for conducting studies with human participants.
arxiv
CTP-LLM: Clinical Trial Phase Transition Prediction Using Large Language Models [PDF]
arXivNew medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final approval. Recent literature indicates that the design of the trial protocols significantly contributes to trial ...
arxiv