Clinical trial metadata:Defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme [PDF]
, 2015 Background: By 2011, the Health Technology Assessment (HTA) programme had published the results of over 100 trials with another 220 in progress. The aim of the project was to develop and pilot ‘metadata’ on clinical trials funded by the HTA programme.
Cook, Andrew +6 more
core +2 more sources
A systematic review of school-based alcohol and other drug prevention programs [PDF]
, 2015 Background: Alcohol use in adolescents constitutes a major public health concern. Europe is the heaviest drinking region of the world. Several school-based alcohol prevention programs have been developed but it is not clear whether they are really ...
Agabio R +5 more
core +1 more source
Continuous Positive Airway Pressure Treatment in Patients with Alzheimer's Disease: A Systematic Review [PDF]
, 2020 Background: Epidemiological studies have suggested a pathophysiological relationship between obstructive sleep apnea syndrome (OSAS) and Alzheimer's disease (AD).
Galán Mercant, Alejandro +5 more
core +2 more sources
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]
, 2011 BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton +6 more
core +1 more source
Safety of short-term dual antiplatelet therapy after drug-eluting stents:An updated meta-analysis with direct and adjusted indirect comparison of randomized control trials [PDF]
, 2014 Background: Duration of dual antiplatelet therapy (DAPT) following drug-eluting stents (DES) remains controversial and is a topic of ongoing research.
Bulluck, Heerajnarain +3 more
core +1 more source
Regenerative medicine: Stroke survivor and carer views and motivations towards a proposed stem cell clinical trial using placebo neurosurgery [PDF]
, 2018 Background Few studies explore stroke survivor views and motivations towards stem cell therapy (SCT). This qualitative study explores the views and motivations of both stroke survivors and their partners/carers towards a proposed 2-arm Phase III ...
Abhyankar +57 more
core +2 more sources
Management of Aphthous Ulceration with Topical Quercetin: A Randomized Clinical Trial [PDF]
The Journal of Contemporary Dental Practice, 2010 Abstract Aim Recurrent aphthous ulceration is the most commonly known oral mucosal disease. Quercetin is a useful therapeutic agent for the treatment of colitis and gastric ulcer. The objective of this study was to determine the effect of topical application of quercetin in the treatment of minor aphthous ulcers.
Mohamed Abd El-Moneam Ibrahem +1 more
openaire +2 more sources
Everolimus as first line therapy for pancreatic neuroendocrine tumours: current knowledge and future perspectives [PDF]
, 2017 urpose Everolimus has been shown to be effective for advanced pancreatic neuroendocrine tumours (pNETs), but its positioning in the therapeutic algorithm for pNETs is matter of debate.
Badalamenti, G. +7 more
core +1 more source
Systematic differences between Cochrane and non-Cochrane meta-analyses on the same topic: a matched pair analysis [PDF]
, 2017 BACKGROUND: Meta-analyses conducted via the Cochrane Collaboration adhere to strict methodological and reporting standards aiming to minimize bias, maximize transparency/reproducibility, and improve the accuracy of summarized data.
Ameli, Omid +6 more
core +9 more sources
An evidence map of the effect of Tai Chi on health outcomes. [PDF]
, 2016 BackgroundThis evidence map describes the volume and focus of Tai Chi research reporting health outcomes. Originally developed as a martial art, Tai Chi is typically taught as a series of slow, low-impact movements that integrate the breath, mind, and ...
Beroes, Jessica M +6 more
core +1 more source