Results 11 to 20 of about 608,159 (405)
A summary of current NKG2D-based CAR clinical trials
Immunotherapy Advances, 2021 Summary Cancer immunotherapies have significantly improved patient survival and treatment options in recent years. Nonetheless, the success of immunotherapy is limited to certain cancer types and specific subgroups of patients, making the development of ...
Sophie Curio +2 more
semanticscholar +1 more source
The Bayesian Design of Adaptive Clinical Trials
International Journal of Environmental Research and Public Health, 2021 This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several disciplines, from a
A. Giovagnoli
semanticscholar +1 more source
Clinical Orthopaedics and Related Research, 2021 Background A lack of racial and ethnic representation in clinical trials may limit the generalizability of the orthopaedic evidence base as it applies to patients in underrepresented minority populations and perpetuate existing disparities in use ...
T. Cwalina +4 more
semanticscholar +1 more source
International Brazilian Journal of Urology, 2022 Introduction: We aimed to evaluate the role of remote proctoring during the initial training phases of a robotics curriculum using surgical robot skills simulator exercises.
Arie Carneiro +6 more
doaj +1 more source
Molecular targets and gene therapy of lung cancer [PDF]
Archive of Oncology, 2009 Lung cancer is of great interest in human pathology because its apparent aggressiveness cannot be stopped by applied treatment procedures. The lack of highly specific screening tests prevents an early diagnosis of the disease.
Vasić Ljiljana
doaj +1 more source
Profile of clinical research related to orthopedic disorders in the last five years
Journal of the Foot & Ankle, 2022 Objective: The aim of the study was to identify the profile of clinical research related to orthopedic disorders worldwide. Methods: A survey of clinical research in orthopedics was performed in the ClinicalTrials.gov platform and Plataforma Brasil ...
Luis Lopez Martinez +5 more
doaj +1 more source
SPOT: Sequential Predictive Modeling of Clinical Trial Outcome with Meta-Learning [PDF]
ACM International Conference on Bioinformatics, Computational Biology and Biomedicine, 2023 Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing trial outcome
Zifeng Wang, Cao Xiao, Jimeng Sun
semanticscholar +1 more source
Systematic differences between Cochrane and non-Cochrane meta-analyses on the same topic: a matched pair analysis [PDF]
, 2015 BACKGROUND: Meta-analyses conducted via the Cochrane Collaboration adhere to strict methodological and reporting standards aiming to minimize bias, maximize transparency/reproducibility, and improve the accuracy of summarized data.
Ameli, Omid +6 more
core +11 more sources
Frontiers in Genetics, 2022 What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients ...
Flavio D’Abramo +4 more
doaj +1 more source
Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]
, 2009 Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Association of British Pharmaceutical Industries +23 more
core +3 more sources