Results 11 to 20 of about 635,069 (409)

The Bayesian Design of Adaptive Clinical Trials

International Journal of Environmental Research and Public Health, 2021
This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several disciplines, from a
A. Giovagnoli
semanticscholar   +1 more source

Is Our Science Representative? A Systematic Review of Racial and Ethnic Diversity in Orthopaedic Clinical Trials from 2000 to 2020

Clinical Orthopaedics and Related Research, 2021
Background A lack of racial and ethnic representation in clinical trials may limit the generalizability of the orthopaedic evidence base as it applies to patients in underrepresented minority populations and perpetuate existing disparities in use ...
T. Cwalina, T. Jella, G. Manyak, Andy Kuo, A. Kamath   +4 more
semanticscholar   +1 more source

Topical Lidocaine plus Diclofenac as a Local Anesthetic Agent in Central Venous Catheterization; a Randomized Controlled Clinical Trial.

Archives of academic emergency medicine, 2021
Various methods of analgesia can be used to reduce or prevent procedural pain in emergency department (ED). This study aimed to evaluate the effectiveness of topical lidocaine-diclofenac combination compared to lidocaine-prilocaine combination (Xyla-P) in reduction of the pain during central venous catheter (CVC) insertion.In this randomized clinical ...
Azizkhani, Reza, Shahnazari Sani, Maysameh, Heydari, Farhad, Saber, Mina, Mousavi, Sarah   +4 more
openaire   +3 more sources

Molecular targets and gene therapy of lung cancer [PDF]

Archive of Oncology, 2009
Lung cancer is of great interest in human pathology because its apparent aggressiveness cannot be stopped by applied treatment procedures. The lack of highly specific screening tests prevents an early diagnosis of the disease.
Vasić Ljiljana
doaj   +1 more source

Systematic differences between Cochrane and non-Cochrane meta-analyses on the same topic: a matched pair analysis [PDF]

, 2015
BACKGROUND: Meta-analyses conducted via the Cochrane Collaboration adhere to strict methodological and reporting standards aiming to minimize bias, maximize transparency/reproducibility, and improve the accuracy of summarized data.
Ameli, Omid, Brennan, Alana, Gill, Christopher J., LaValley, Michael, Reinen, Nichole, Useem, Johanna, Vickery, Michelle   +6 more
core   +11 more sources

Can remote assistance for robotic surgery improve surgical performance in simulation training? A prospective clinical trial of urology residents using a simulator in south america

International Brazilian Journal of Urology, 2022
Introduction: We aimed to evaluate the role of remote proctoring during the initial training phases of a robotics curriculum using surgical robot skills simulator exercises.
Arie Carneiro, Oliver Rojas Claros, Jonathan Doyun Cha, Paulo Priante Kayano, Marcelo Apezzato, Andrew Aurel Wagner, Gustavo Caserta Lemos   +6 more
doaj   +1 more source

Effect of topical anticholinergic medication on clinical manifestations control among patients with vasomotor rhinitis versus allergic rhinitis: as comparative clinical trials

The Egyptian Journal of Otolaryngology, 2023
Abstract Background The use of a topical anticholinergic medication, ipratropium bromide, and its ability to inhibit methacholine and rhinitis-induced hypersecretion is emphasized. Ipratropium bromide appears to be both safe and effective in reducing this troublesome symptom.
Anas Mohamed Askoura, Sabry Magdy Sabry, Samia Ahmed Fawaz, Manal Ibrahim Salman, Moustafa Ahmed Mahmoud Anter El sordy, Ossama Mustafa Mady   +5 more
openaire   +2 more sources

Profile of clinical research related to orthopedic disorders in the last five years

Journal of the Foot & Ankle, 2022
Objective: The aim of the study was to identify the profile of clinical research related to orthopedic disorders worldwide. Methods: A survey of clinical research in orthopedics was performed in the ClinicalTrials.gov platform and Plataforma Brasil ...
Luis Lopez Martinez, Caio de Oliveira Candido, Vinicius da Silva Naresse, Bruno Carraro Lolo, Silvonete Lima dos Santos, Alexandre Leme Godoy-Santos   +5 more
doaj   +1 more source

Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research

Frontiers in Genetics, 2022
What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients ...
Flavio D’Abramo, Flavio D’Abramo, Flavio D’Abramo, Annemieke Bont, Lisa Nüßlein   +4 more
doaj   +1 more source

Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]

, 2009
Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Association of British Pharmaceutical Industries, British Medical Association, Christine Kerr, Clinical Research Report, D Fayter, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, Department of Health, General Medical Council, J Bryant, James Raftery, John Powell, ME Charlson, Medical Research Council, Nvivo, RJ Prescott, S Asch, S Hawker, Sheila Hawker, V Peto, WJ Jack   +23 more
core   +3 more sources