Results 11 to 20 of about 332,732 (168)

Topical Tacrolimus as an adjunct to Conventional Therapy for Stromal Herpetic Keratitis: a Randomized Clinical Trial

Journal of Ophthalmic and Vision Research, 2019
Purpose: This study investigates the effects of 0.05% topical tacrolimus as an adjunct therapy for patients with non-necrotizing herpetic stromal keratitis (HSK). Methods: Patients with non-necrotizing HSK, referred to the Cornea Clinic at Hospital in Rasht, Iran, between September 2016 and February 2018, were randomly assigned to two groups. The case
Mitra Akbari, Reza Soltani Moghadam, Ramin Elmi, Amir Nosrati, Ehsan Taghiabadi, Nasser Aghdami   +5 more
openaire   +4 more sources

Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers

JAMA Network Open, 2023
ImportancePreclinical and phase 1/2 studies with esmolol hydrochloride suggest its potential role in treatment of diabetic foot ulcers (DFUs).ObjectiveTo study the efficacy of topical esmolol for healing of uninfected DFUs.Design, Setting, and ParticipantsA randomized, double-blind, multicenter, phase 3 clinical trial was conducted from December 26 ...
Ashu, Rastogi, Sudhir A, Kulkarni, Sanjay, Agarwal, Murtaza, Akhtar, Sachin, Arsule, Sudhir, Bhamre, Deepak, Bhosle, Sanjay, Desai, Manisha, Deshmukh, K V, Giriraja, Jagannath, Jagannath, Reema Yuvraj, Kashiva, Rajesh, Kesavan, Deepak, Khandelwal, Sanjay, Kolte, Srikanth, Kongara, Anil Kumar, Darivemula, C, Madhusudan, Mohammad Asif Haji, Pyare Saheb Qureshi, Muthu, Ramu, Gunvant, Rathod, Sadasiva Rao, Yalamanchi, Shobhit, Shakya, Prathvi, Shetty, Sudagar, Singh, Supreet K, Deshpande, Vijay, Viswanathan, Ambika G, Unnikrishnan   +27 more
openaire   +2 more sources

Current evidence linking polyunsaturated fatty acids (PUFAs) with cancer risk and progression

Frontiers in Oncology, 2013
There is increasing evidence that polyunsaturated fatty acids (PUFAs) play a role in cancer risk and progression. The n-3 family of PUFAs includes alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) while the n-6 family
Maria eAzrad, Chelsea Elizabeth Turgeon, Wendy eDemark-Wahnefried   +2 more
doaj   +1 more source

A European Approach to Clinical Investigator Training

Frontiers in Pharmacology, 2013
A better education and training of clinical investigators and their teams is one of the factors that could foster the development of clinical research in Europe, a key objective of the Innovative Medicines Initiative (IMI).
Jean-Marie eBoeynaems, Cindy eCanivet, Anthony eChan, Mary Jane eClark, Catherine eCornu, Esther eDaemen, Jacques eDemotes, Katelijne eDe Nys, Barry eHirst, Ferdinand eHundt, Behrouz eKassai, Sandor - Kerpel-Fronius, Lucy eKiessig, Heinrich eKlech, Jean-Pierre eKraehenbuhl, Pierre eLafolie, Martin eLucht, Detlef eNiese, Christiane ePauli-Magnus, Barbara ePeters, Ralf eSchaltenbrand, Armel eStockis, Martina eStykova, Nicolette eVerheus, Ingrid eKlingmann   +24 more
doaj   +1 more source

Pulmonary Hypertension Association's 2022 International Conference Scientific Sessions Overview

Pulmonary Circulation, 2023
The considerable progress made in recent years in the diagnosis, risk stratification, and treatment of pulmonary hypertension was highlighted during the most recent edition of the Pulmonary Hypertension Association Scientific Sessions, which was held in ...
Ayedh K. Alamri, Nicholas J. Shelburne, Jennalyn D. Mayeux, Evan Brittain   +3 more
doaj   +1 more source

How can we associate an economic evaluation with a clinical trial? [PDF]

Brazilian Oral Research
Economic evaluations in Dentistry have been increasing in recent years. They are a relevant contribution if an economic issue exists. Knowing if a new intervention is an efficient way of allocating available (and scarce) resources (the concept of ...
Mariana Minatel BRAGA, Gabriela Manco MACHADO, Elizabeth Souza ROCHA, Maria Eduarda VIGANÓ, Laura Regina Antunes PONTES, Daniela Prócida RAGGIO   +5 more
doaj   +2 more sources

Protecting intellectual property associated with Canadian academic clinical trials - approaches and impact

Trials, 2012
Intellectual property is associated with the creative work needed to design clinical trials. Two approaches have developed to protect the intellectual property associated with multicentre trial protocols prior to site initiation.
Ross Sue, Magee Laura, Walker Mark, Wood Stephen   +3 more
doaj   +1 more source

A systematic review of the processes used to link clinical trial registrations to their published results

Systematic Reviews, 2017
Background Studies measuring the completeness and consistency of trial registration and reporting rely on linking registries with bibliographic databases. In this systematic review, we quantified the processes used to identify these links. Methods PubMed
Rabia Bashir, Florence T. Bourgeois, Adam G. Dunn   +2 more
doaj   +1 more source

Reproducibility of ambulatory blood pressure changes from the initial values on two different days

Clinics, 2013
OBJECTIVE: We tested the reproducibility of changes in the ambulatory blood pressure (BP) from the initial values, an indicator of BP reactivity and cardiovascular health outcomes, in young, healthy adults.
Garrett I. Ash, Timothy J. Walker, Kayla M. Olson, Jeffrey H. Stratton, Ana L. Gomez, William J. Kraemer, Jeff S. Volek, Linda S. Pescatello   +7 more
doaj   +1 more source

A comparative randomized clinical trial evaluating the efficacy and safety of tacrolimus versus hydrocortisone as a topical treatment of atopic dermatitis in children

Frontiers in Pharmacology, 2023
Background: Atopic dermatitis (AD) aetiology is not exactly identified, but it is characterized by pruritic skin reactions with elevation in the levels of inflammatory markers. Despite the fact that Corticosteroids are the mainstay therapy in the management of AD, they have many local and systemic adverse effects.Objective: The aim of this study is to ...
Amal A. Mohamed, Radwa El Borolossy, Eman M. Salah, Maha S. Hussein, Nashwa M. Muharram, Naglaa Elsalawy, Mona G. Khalil, Maha O. Mahmoud, Reham Y. El-Amir, Heba M. A. Elsanhory, Nourelhuda Ahmed, Ahmed S. Adaroas, Mahmoud Montaser, Amal A. El Kholy   +13 more
openaire   +3 more sources