Results 31 to 40 of about 1,905,942 (404)

A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)

Journal of Applied Oral Science, 2010
INTRODUCTION: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which ...
Raphael Freitas de Souza, Carolina de Andrade Lima Chaves, Mona Nasser, Zbys Fedorowicz   +3 more
doaj   +1 more source

Trends and Features of the Applications of Natural Language Processing Techniques for Clinical Trials Text Analysis

Applied Sciences, 2020
Natural language processing (NLP) is an effective tool for generating structured information from unstructured data, the one that is commonly found in clinical trial texts.
Xieling Chen, Haoran Xie, G. Cheng, Leonard K. M. Poon, Mingming Leng, F. Wang   +5 more
semanticscholar   +1 more source

Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing [PDF]

, 2023
In the UK, the Medicines and Healthcare products Regulatory Agency consulted on proposals “to improve and strengthen the UK clinical trials legislation to help us make the UK the best place to research and develop safe and innovative medicines”.
Choodari-Oskooei, Babak, Couturier, Dominique-Laurent, Crout, Phillip, Gamble, Carrol, Jacko, Peter, Jaki, Thomas, Law, Martin, Pallmann, Philip, Pilling, Mark, Robertson, David S, Robling, Michael, Sydes, Matthew R, Villar, Sofía S, Wason, James, Wheeler, Graham, Williamson, S Faye, Yap, Christina   +16 more
core  

Centre selection for clinical trials and the generalisability of results: a mixed methods study. [PDF]

, 2013
BACKGROUND: The rationale for centre selection in randomised controlled trials (RCTs) is often unclear but may have important implications for the generalisability of trial results.
A Britton, A Manca, A Manca, A Manca, Adrian Gheorghe, AW Hoel, Benjamin R. Fletcher, BJ O’Brien, C Bartlett, DA Moore, DJ Costa, EA Halm, ER DeLong, FEKDJ Kraemer Hc, HF Hsieh, I Boutron, I Jacquier, Isabelle Boutron, Jonathan C. Ives, JT Braslow, KE Thorpe, L Maasland, M Calvert, M Drummond, M Sandelowski, ME Falagas, Melanie Calvert, MF Drummond, P Kalata, PM Rothwell, RE Glasgow, RL Kravitz, RMD Smyth, S Al-Marzouki, S Eldridge, SD Ramsey, SL Silverman, SR Tunis, Tracy E. Roberts   +38 more
core   +3 more sources

Current evidence linking polyunsaturated fatty acids (PUFAs) with cancer risk and progression

Frontiers in Oncology, 2013
There is increasing evidence that polyunsaturated fatty acids (PUFAs) play a role in cancer risk and progression. The n-3 family of PUFAs includes alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) while the n-6 family
Maria eAzrad, Chelsea Elizabeth Turgeon, Wendy eDemark-Wahnefried   +2 more
doaj   +1 more source

A Clinical Trial of Fluperolone: A New Topical Steroid [PDF]

Postgraduate Medical Journal, 1963
ALLOTT, E. N., and SKELTON, M. 0. (I960): Increased Adrenocortical Activity Associated with Malignant Disease, Lancet, ii, 278. BAGSHAWE, K. D. (ig6oa): Hypokalsemia, Carcinoma and Cushing's Syndrome, Ibid., ii, 284. (ig6ob): Hyperfunction of the Adrenal Cortex with Adrenal Metastases, Ibid., ii, 287. REES, J. R., ROSALKI, S. B., and MACLEAN, A. D. W. (
openaire   +2 more sources

The Effect of Sodium Hypochlorite and Chlorhexidine as Irrigant Solutions for Root Canal Disinfection: A Systematic Review of Clinical Trials [PDF]

, 2016
Introduction This systematic review aimed to compare the effectiveness of sodium hypochlorite and chlorhexidine for root canal disinfection during root canal therapy.
Andrade Junior, C.V., Gonçalves, L.S., Rodrigues, R.C.V., Soares, R.G., Vettore, M.   +4 more
core   +1 more source

A European Approach to Clinical Investigator Training

Frontiers in Pharmacology, 2013
A better education and training of clinical investigators and their teams is one of the factors that could foster the development of clinical research in Europe, a key objective of the Innovative Medicines Initiative (IMI).
Jean-Marie eBoeynaems, Cindy eCanivet, Anthony eChan, Mary Jane eClark, Catherine eCornu, Esther eDaemen, Jacques eDemotes, Katelijne eDe Nys, Barry eHirst, Ferdinand eHundt, Behrouz eKassai, Sandor - Kerpel-Fronius, Lucy eKiessig, Heinrich eKlech, Jean-Pierre eKraehenbuhl, Pierre eLafolie, Martin eLucht, Detlef eNiese, Christiane ePauli-Magnus, Barbara ePeters, Ralf eSchaltenbrand, Armel eStockis, Martina eStykova, Nicolette eVerheus, Ingrid eKlingmann   +24 more
doaj   +1 more source

Treatment Effect Quantification for Time-to-event Endpoints -- Estimands, Analysis Strategies, and beyond [PDF]

Pharm Stat, 2019, 18, 144-164, 2017
A draft addendum to ICH E9 has been released for public consultation in August 2017. The addendum focuses on two topics particularly relevant for randomized confirmatory clinical trials: estimands and sensitivity analyses. The need to amend ICH E9 grew out of the realization of a lack of alignment between the objectives of a clinical trial stated in ...
arxiv   +1 more source

Topical Licorice for Aphthous: A Systematic Review of Clinical Trials.

Iranian journal of medical sciences, 2023
Recurrent aphthous stomatitis (RAS) is the most common ulcerative disease that affects oral mucosa. The coating agents, topical analgesics, and topical steroids are usually used as treatment methods. Glycyrrhiza glabra has been used for RAS treatment based on its anti-inflammatory, antioxidant, and immunomodulatory properties. In this study, a systemic
Fereshteh Dorsareh, Gita Vahid-Dastjerdi, Abdelhakim Bouyahya, Mohammad Mehdi Zarshenas, Mostafa Rezaie, Woong Yang, Ehsan Amiri-Ardekani   +6 more
openaire   +3 more sources