Results 31 to 40 of about 635,069 (409)

Topical Tacrolimus as an adjunct to Conventional Therapy for Stromal Herpetic Keratitis: a Randomized Clinical Trial

Journal of Ophthalmic and Vision Research, 2019
Purpose: This study investigates the effects of 0.05% topical tacrolimus as an adjunct therapy for patients with non-necrotizing herpetic stromal keratitis (HSK). Methods: Patients with non-necrotizing HSK, referred to the Cornea Clinic at Hospital in Rasht, Iran, between September 2016 and February 2018, were randomly assigned to two groups. The case
Mitra Akbari, Reza Soltani Moghadam, Ramin Elmi, Amir Nosrati, Ehsan Taghiabadi, Nasser Aghdami   +5 more
openaire   +4 more sources

Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers

JAMA Network Open, 2023
ImportancePreclinical and phase 1/2 studies with esmolol hydrochloride suggest its potential role in treatment of diabetic foot ulcers (DFUs).ObjectiveTo study the efficacy of topical esmolol for healing of uninfected DFUs.Design, Setting, and ParticipantsA randomized, double-blind, multicenter, phase 3 clinical trial was conducted from December 26 ...
Ashu, Rastogi, Sudhir A, Kulkarni, Sanjay, Agarwal, Murtaza, Akhtar, Sachin, Arsule, Sudhir, Bhamre, Deepak, Bhosle, Sanjay, Desai, Manisha, Deshmukh, K V, Giriraja, Jagannath, Jagannath, Reema Yuvraj, Kashiva, Rajesh, Kesavan, Deepak, Khandelwal, Sanjay, Kolte, Srikanth, Kongara, Anil Kumar, Darivemula, C, Madhusudan, Mohammad Asif Haji, Pyare Saheb Qureshi, Muthu, Ramu, Gunvant, Rathod, Sadasiva Rao, Yalamanchi, Shobhit, Shakya, Prathvi, Shetty, Sudagar, Singh, Supreet K, Deshpande, Vijay, Viswanathan, Ambika G, Unnikrishnan   +27 more
openaire   +2 more sources

Analyzing differences in the costs of treatment across centers within economic evaluations [PDF]

, 2001
Objectives: Assessments of health technologies increasingly include economic evaluations conducted alongside clinical trials. One particular concern with economic evaluations conducted alongside clinical trials is the generalizability of results from one
Coyle, D, Drummond, M F
core   +1 more source

Current evidence linking polyunsaturated fatty acids (PUFAs) with cancer risk and progression

Frontiers in Oncology, 2013
There is increasing evidence that polyunsaturated fatty acids (PUFAs) play a role in cancer risk and progression. The n-3 family of PUFAs includes alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) while the n-6 family
Maria eAzrad, Chelsea Elizabeth Turgeon, Wendy eDemark-Wahnefried   +2 more
doaj   +1 more source

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton, Cheng-Fang Hsieh, Gillian E Mead, Graeme J Hankey, Mansur A Kutlubaev, Maree L Hackett, Rebecca Lee   +6 more
core   +1 more source

A European Approach to Clinical Investigator Training

Frontiers in Pharmacology, 2013
A better education and training of clinical investigators and their teams is one of the factors that could foster the development of clinical research in Europe, a key objective of the Innovative Medicines Initiative (IMI).
Jean-Marie eBoeynaems, Cindy eCanivet, Anthony eChan, Mary Jane eClark, Catherine eCornu, Esther eDaemen, Jacques eDemotes, Katelijne eDe Nys, Barry eHirst, Ferdinand eHundt, Behrouz eKassai, Sandor - Kerpel-Fronius, Lucy eKiessig, Heinrich eKlech, Jean-Pierre eKraehenbuhl, Pierre eLafolie, Martin eLucht, Detlef eNiese, Christiane ePauli-Magnus, Barbara ePeters, Ralf eSchaltenbrand, Armel eStockis, Martina eStykova, Nicolette eVerheus, Ingrid eKlingmann   +24 more
doaj   +1 more source

Clinical trial metadata:Defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme [PDF]

, 2015
Background:  By 2011, the Health Technology Assessment (HTA) programme had published the results of over 100 trials with another 220 in progress. The aim of the project was to develop and pilot ‘metadata’ on clinical trials funded by the HTA programme.  
Cook, Andrew, Davidson, Peter, Milne, Ruairidh, Raftery, James, Stanton, Louise, Turner, David, Young, Amanda   +6 more
core   +2 more sources

How can we associate an economic evaluation with a clinical trial? [PDF]

Brazilian Oral Research
Economic evaluations in Dentistry have been increasing in recent years. They are a relevant contribution if an economic issue exists. Knowing if a new intervention is an efficient way of allocating available (and scarce) resources (the concept of ...
Mariana Minatel BRAGA, Gabriela Manco MACHADO, Elizabeth Souza ROCHA, Maria Eduarda VIGANÓ, Laura Regina Antunes PONTES, Daniela Prócida RAGGIO   +5 more
doaj   +2 more sources

Protecting intellectual property associated with Canadian academic clinical trials - approaches and impact

Trials, 2012
Intellectual property is associated with the creative work needed to design clinical trials. Two approaches have developed to protect the intellectual property associated with multicentre trial protocols prior to site initiation.
Ross Sue, Magee Laura, Walker Mark, Wood Stephen   +3 more
doaj   +1 more source

An evidence map of the effect of Tai Chi on health outcomes. [PDF]

, 2016
BackgroundThis evidence map describes the volume and focus of Tai Chi research reporting health outcomes. Originally developed as a martial art, Tai Chi is typically taught as a series of slow, low-impact movements that integrate the breath, mind, and ...
Beroes, Jessica M, Hempel, Susanne, Miake-Lye, Isomi M, Shanman, Roberta M, Shekelle, Paul G, Solloway, Michele R, Taylor, Stephanie L   +6 more
core   +1 more source