Results 41 to 50 of about 612,154 (364)

Choosing and using methodological search filters : searchers' views [PDF]

, 2015
© 2014 The authors.
Beale, Sophie, Boachie, Charles, Duffy, Steven, Fraser, Cynthia, Glanville, Julie, Harbour, Jenny, Lefebvre, Carol, McCool, Rachael, Smith, Lynne, Varley, Danielle, Wright, Dianne   +10 more
core   +1 more source

Optimal search strategies for identifying sound clinical prediction studies in EMBASE [PDF]

, 2005
BACKGROUND: Clinical prediction guides assist clinicians by pointing to specific elements of the patient's clinical presentation that should be considered when forming a diagnosis, prognosis or judgment regarding treatment outcome.
A Laupacis, AG Randolph, AR Jadad, BJ Ingui, BT Walsh, CE Adams, FA McAlister, Jennifer L Holland, JF Steiner, JH Wasson, JI Emparanza, JW Ely, LM Bachmann, LM Bachmann, Nancy L Wilczynski, NL Wilczynski, NL Wilczynski, NL Wilczynski, PS Wells, R Brian Haynes, RB Haynes, RB Haynes, RJ Watson, SS Wong, T McGinn, TG McGinn   +25 more
core   +3 more sources

Does soy protein supplementation affect body composition in healthy exerciser adults? A systematic review and meta-analysis of clinical trials [PDF]

, 2019
Background objectives: The effects of soy protein supplementation on anthropometric parameters and body composition indices of healthy adults is equivocal.
Asbaghi, O., Clark, C.C.T., Falahi, E., Jafarnejad, S., Khosroshahi, M.Z., Rad, E.Y., Saboori, S.   +6 more
core   +3 more sources

Targeting mTOR in Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2016
Treatment options for advanced pancreatic ductal adenocarcinoma (PDAC) are limited, however, new therapies targeting specific tumor-related molecular characteristics may help certain patient cohorts. Emerging preclinical data has shown that inhibition of
Sentia eIriana, Shahzad eAhmed, Jun eGong, Jun eGong, Alagappan Anand Annamalai, Richard eTuli, Andrew Eugene Hendifar   +6 more
doaj   +1 more source

Inadequate reporting quality of registered genome editing trials: an observational study

BMC Medical Research Methodology, 2022
Background To assess registration completeness and safety data of trials on human genome editing (HGE) reported in primary registries and published in journals, as HGE has safety and ethical problems, including the risk of undesirable and unpredictable ...
Diana Jurić, Michael Zlatin, Ana Marušić   +2 more
doaj   +1 more source

Regenerative medicine: Stroke survivor and carer views and motivations towards a proposed stem cell clinical trial using placebo neurosurgery [PDF]

, 2018
Background  Few studies explore stroke survivor views and motivations towards stem cell therapy (SCT). This qualitative study explores the views and motivations of both stroke survivors and their partners/carers towards a proposed 2-arm Phase III ...
Abhyankar, Abhyankar, Abhyankar, Aked, Akinsanya, Alaszewski, Alfred, Anderson, Bekker, Bell, Bowling, Braun, Brown, Campbell, Connell, Coolbrandt, Dekkers, Dixon-Woods, Donovan, Donovan, Donovan, Donovan, Entwhistle, Exel, Gillies, Goetz, Greenwood, Guba, Guest, Illingworth, Juraskova, King, Knebly, Lidz, Liu, Lo, Luker, Madse, McCann, McDonald, Miles, Mills, Moorcraft, Paolucci, Rigby, Ritchie, Robinson, Sagi, Savitz, Secrest, Sinden, Singer, Stroke Association, Swift, Treweek, Welton, West, World Medical Association   +57 more
core   +3 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Exosomes and Immune Response in Cancer: Friends or Foes?

Frontiers in Immunology, 2018
Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent years. This led to the understanding that these structures, far from being inert waste by-products of cellular functioning, are active players in intercellular ...
Francisco M. Barros, Fatima Carneiro, Fatima Carneiro, Fatima Carneiro, Fatima Carneiro, Jose C. Machado, Jose C. Machado, Jose C. Machado, Sónia A. Melo, Sónia A. Melo, Sónia A. Melo   +10 more
doaj   +1 more source

An alternative approach to deal with the absence of clinical trials: a proportional meta-analysis of case series studies [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: Systematic reviews are criticized for frequently offering inconsistent evidences and absence of straightforward recommendations. Their value seems to be depreciated when the conclusions are uncertain.
Regina El Dib, Paulo Nascimento Junior, Anil Kapoor   +2 more
doaj   +2 more sources

“It’s trying to manage the work” : A qualitative evaluation of recruitment processes within a UK multi-centre trial [PDF]

, 2017
Acknowledgments The authors would like to thank all interviewees who agreed to take part in this study. The authors would like to thank the TISU Trial Group for their support with this project. In particular, the authors would like to thank Sarah Cameron
Gillies, Katie, Skea, Zoe Christina, Treweek, Shaun   +2 more
core   +1 more source