Results 41 to 50 of about 1,662,629 (361)
How can we associate an economic evaluation with a clinical trial? [PDF]
Brazilian Oral ResearchEconomic evaluations in Dentistry have been increasing in recent years. They are a relevant contribution if an economic issue exists. Knowing if a new intervention is an efficient way of allocating available (and scarce) resources (the concept of ...
Mariana Minatel BRAGA +5 more
doaj +2 more sources
Trials, 2012 Intellectual property is associated with the creative work needed to design clinical trials. Two approaches have developed to protect the intellectual property associated with multicentre trial protocols prior to site initiation.
Ross Sue +3 more
doaj +1 more source
The Optimal Design of Clinical Trials with Potential Biomarker Effects, A Novel Computational Approach [PDF]
, 2020 As a future trend of healthcare, personalized medicine tailors medical treatments to individual patients. It requires to identify a subset of patients with the best response to treatment. The subset can be defined by a biomarker (e.g. expression of a gene) and its cutoff value. Topics on subset identification have received massive attention.
arxiv +1 more source
Artificial Intelligence for In Silico Clinical Trials: A Review [PDF]
arXiv, 2022 A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials. AI-enabled in silico trials can increase the case group size by creating virtual cohorts as controls. In addition,
arxiv
Systematic Reviews, 2017 Background Studies measuring the completeness and consistency of trial registration and reporting rely on linking registries with bibliographic databases. In this systematic review, we quantified the processes used to identify these links. Methods PubMed
Rabia Bashir +2 more
doaj +1 more source
Reproducibility of ambulatory blood pressure changes from the initial values on two different days
Clinics, 2013 OBJECTIVE: We tested the reproducibility of changes in the ambulatory blood pressure (BP) from the initial values, an indicator of BP reactivity and cardiovascular health outcomes, in young, healthy adults.
Garrett I. Ash +7 more
doaj +1 more source
Management of Aphthous Ulceration with Topical Quercetin: A Randomized Clinical Trial [PDF]
The Journal of Contemporary Dental Practice, 2010 Abstract Aim Recurrent aphthous ulceration is the most commonly known oral mucosal disease. Quercetin is a useful therapeutic agent for the treatment of colitis and gastric ulcer. The objective of this study was to determine the effect of topical application of quercetin in the treatment of minor aphthous ulcers.
Mohamed Abd El-Moneam Ibrahem +1 more
openaire +2 more sources
Frontiers in Neurology, 2016 Background: This paper introduces a tool for streamlining data integration in rehabilitation science, the Centralized Open-Access Rehabilitation database for Stroke (SCOAR), which allows researchers to quickly visualize relationships among variables ...
Keith Lohse +5 more
doaj +1 more source
Pulmonary Hypertension Association's 2022 International Conference Scientific Sessions Overview
Pulmonary Circulation, 2023 The considerable progress made in recent years in the diagnosis, risk stratification, and treatment of pulmonary hypertension was highlighted during the most recent edition of the Pulmonary Hypertension Association Scientific Sessions, which was held in ...
Ayedh K. Alamri +3 more
doaj +1 more source