Results 71 to 80 of about 55,609,055 (315)

Topic-specific living databases of clinical trials: A scoping review of public databases

open access: yes
INTRODUCTION Conducting systematic reviews of clinical trials is time-consuming and resource-intensive. One potential solution is to design databases that are continuously and automatically populated with clinical trial data from harmonised and ...
Hirt, Julian   +3 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Can implant surfaces affect implant stability during osseointegration? A randomized clinical trial

open access: yesBrazilian Oral Research, 2018
This randomized clinical trial evaluated the insertion torque (IT), primary, and secondary stability of dental implants with different surface treatments during the osseointegration period.
Luiz Carlos do CARMO FILHO   +4 more
doaj   +1 more source

Research Report 2008–2009 [PDF]

open access: yes, 2010
The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, takes part in trials of national and international collaborative trial groups and contributes expertise to trials run by others ...
NHMRC Clinical Trials Centre
core  

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Mapping the evolving definitions of translational research

open access: yesJournal of Clinical and Translational Science, 2017
Objective Systematic review and analysis of definitions of translational research. Materials and methods The final corpus was comprised of 33 papers, each
Daniel G. Fort   +4 more
doaj   +1 more source

The role of machine learning in clinical research: transforming the future of evidence generation

open access: yesTrials, 2021
Background Interest in the application of machine learning (ML) to the design, conduct, and analysis of clinical trials has grown, but the evidence base for such applications has not been surveyed.
E. Hope Weissler   +20 more
doaj   +1 more source

Efficacy of topical clotrimazole vs. topical tolnaftate in the treatment of otomycosis. A randomized controlled clinical trial

open access: yesBrazilian Journal of Otorhinolaryngology, 2020
Otomycosis, an infection of the ear canal by fungi, is prevalent in hot and humid weather. Nevertheless, there is not sufficient evidence for the effectiveness of different topical antifungal treatments. Tolnaftate, is a topical antifungal agent described to be effective in the treatment of otomycosis.
Lesly Jimenez-Garcia   +6 more
openaire   +5 more sources

Research Report 2004–2005 [PDF]

open access: yes, 2006
The National Health and Medical Research Council Clinical Trials Centre has the purpose of improving outcomes in health through clinical trials research.
NHMRC Clinical Trials Centre
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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