Plasma Cyclic Guanosine Monophosphate Is a Promising Biomarker of Clinically Significant Portal Hypertension in Patients With Liver Cirrhosis [PDF]
Introduction: Despite intensive research, reliable blood-derived parameters to detect clinically significant portal hypertension (CSPH) in patients with cirrhosis are lacking.
Lukas Sturm +14 more
doaj +3 more sources
THE ROLE OF ELASTOGRAPHY IN CLINICALLY SIGNIFICANT PORTAL HYPERTENSION [PDF]
This is a narrative review that aims to discuss the importance of elastographic methods in the evaluation of clinically significant portal hypertension (CSPH) in cirrhotic patients, where the authors propose an algorithm for evaluating these patients. In
Angelo Alves de MATTOS +4 more
doaj +3 more sources
Aims Portal hypertension (PH) is a complication of cirrhosis that leads to hepatic decompensation. Assessing the portal pressure gradient (PPG) provides valuable information for disease assessment, staging, and prognosis.
Jerome C. Edelson +7 more
doaj +2 more sources
Introduction and Objectives: Primary biliary cholangitis (PBC) may progress to clinically significant portal hypertension (CSPH) before the development of cirrhosis.
Ying Zhang +9 more
doaj +2 more sources
Laparoscopic hepatectomy for hepatocellular carcinoma in patients with clinically significant portal hypertension: a systematic review and meta-analysis [PDF]
Objective To compare the effects of laparoscopic hepatectomy (LH) on the short-term and long-term outcomes in hepatocellular carcinoma (HCC) patients with and without clinically significant portal hypertension (CSPH).
Zhi-qiang Xiang +8 more
doaj +2 more sources
Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements
Portal hypertension, the most common complication in liver cirrhosis, is characterized by a pathologic increase in portal venous pressure. Portal hypertension is defined as a pressure gradient greater than 5 mmHg between the portal vein and the inferior ...
Kathleen Möller +7 more
doaj +2 more sources
Noninvasive Detection of Clinically Significant Portal Hypertension in Compensated Advanced Chronic Liver Disease. [PDF]
Patients with compensated advanced chronic liver disease have different prognoses depending on the presence of portal hypertension. Current non-invasive diagnostic methods allow identification of clinically significant portal hypertension.
Berzigotti, Annalisa +2 more
core +3 more sources
MR elastography outperforms shear wave elastography for the diagnosis of clinically significant portal hypertension. [PDF]
OBJECTIVES Portal hypertension (PH) is associated with complications such as ascites and esophageal varices and is typically diagnosed through invasive hepatic venous pressure gradient (HVPG) measurement, which is not widely available.
Kennedy P +15 more
europepmc +2 more sources
Accuracy of spleen stiffness measurement for the diagnosis of clinically significant portal hypertension in patients with compensated advanced chronic liver disease: a systematic review and individual patient data meta-analysis. [PDF]
BACKGROUND The diagnosis of clinically significant portal hypertension is crucial for prognosis and treatment guidance in patients with compensated advanced chronic liver disease (ACLD).
Elkrief, Laure +19 more
core +2 more sources
Methods for assessing portal hypertension
Many researchers and clinicians have taken the value of hepatic venous pressure gradient (HVPG) as an essential prognostic factor in subjects with chronic liver diseases. HVPG ≥ 10 mmHg indicates the presence of clinically significant portal hypertension,
S.M. Chooklin, S.S. Chuklin
doaj +1 more source

