Results 41 to 50 of about 18,378,232 (237)

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

The Role of Non-Selective β-Blockers in Compensated Cirrhotic Patients without Major Complications

Medicina, 2019
Background and Objectives: Non-selective β-blockers (NSBB) could prevent decompensation and hepatocellular carcinoma (HCC) in cirrhotic patients with clinically significant portal hypertension (CSPH), but remained uncertain for compensated cirrhotic
Wen-Shuo Yeh, Shih-Cheng Yang, Chih-Ming Liang, Yu-Chi Li, Wei-Chen Tai, Chen-Hsiang Lee, Yao-Hsu Yang, Chien-Ning Hsu, Tzu-Hsien Tsai, Seng-Kee Chuah, Cheng-Kun Wu   +10 more
doaj   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

Hepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat, Kieran Hawthorne, Kenneth D. R. Setchell, Monica Narvaez Rivas, Lisa Henn, Charlotte A. Beil, Saul J. Karpen, Vicky L. Ng, Estella M. Alonso, Jorge A. Bezerra, Stephen L. Guthery, Simon Horslen, Kathy M. Loomes, Patrick McKiernan, John C. Magee, Robert M. Merion, Jean P. Molleston, Philip Rosenthal, Richard J. Thompson, Kasper S. Wang, Ronald J. Sokol, Benjamin L. Shneider, for Childhood Liver Disease Research Network (ChiLDReN)   +22 more
wiley   +1 more source

Quantitative computed tomography‐based approaches for noninvasive diagnosis of portal hypertension in patients with cirrhosis

Portal Hypertension & Cirrhosis, 2023
Noninvasive diagnosis of portal hypertension in patients with cirrhosis can be achieved using different methods, including laboratory tests and imaging.
Riccardo Sartoris, Valerie Vilgrain
doaj   +1 more source

El futuro de la elastografía esplénica: ¿es una herramienta útil para el tratamiento personalizado?

Revista de Gastroenterología de México
Resumen: La hipertensión portal es el principal factor determinante del pronóstico en la cirrosis hepática. El estándar de oro para su evaluación es la medición del gradiente de presión venosa hepática. Sin embargo, se trata de una prueba invasiva que se
D.K. Tapia Calderón, E. Llop Herrera, J.L. Calleja Panero, E.S. García Jiménez, G. Castro Narro, J.A. Velarde-Ruiz Velasco   +5 more
doaj   +1 more source

Influence of Gut–Liver Axis on Portal Hypertension in Advanced Chronic Liver Disease: The Gut Microbiome as a New Protagonist in Therapeutic Management

Microbiology Research, 2022
Clinically significant portal hypertension is associated with most complications of advanced chronic liver disease (ACLD), including variceal bleeding, ascites, spontaneous bacterial peritonitis, hepatorenal syndrome, and hepatic encephalopathy.
Francesco Santopaolo, Gaetano Coppola, Lucia Giuli, Antonio Gasbarrini, Francesca Romana Ponziani   +4 more
doaj   +1 more source

Non-invasive assessment and prediction of clinically significant portal hypertension

, 2011
Hepatic venous pressure gradient (HVPG) predicts variceal development, bleeding, clinical decompensation and death. Measurement is invasive, time-consuming and performed in few centres.
Austin, Andrew, K. Rye, A. Austin, Freeman, Jan G., J. Freeman, G. Mortimore, Rye, Kara, Mortimore, Gerri   +7 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Portal Hypertension Secondary to Benign Prostatic Hyperplasia

, 2022
Benign prostatic hyperplasia (BPH) obstructs the bladder outlet. Patients with BPH frequently present with lower urinary tract symptoms. However, patients with BPH can present with serious fatal complications unless diagnosed and treated sufficiently. In
Emrullah Söğütdelen, Adnan Gücük, Sebahat Gücük, Mustafa Küçükyangöz   +3 more
core   +1 more source

Baveno Criteria Spare Endoscopies Among Patients With Compensated Cirrhosis Within a Large US Healthcare System

Gastro Hep Advances
Background and Aims: The Baveno criteria have been validated in populations outside of the United States and have been shown to accurately rule out clinically significant portal hypertension (CSPH) and high-risk varices. The criteria have been adopted by
Marcia Leung, Mehrnaz Siavoshi, Nathan Billet, Xiaoran Li, Elijah Wade, Sreepriya Balasubramanian, Varun Saxena, Suk Seo, Krisna Chai, Brock MacDonald, Jeffrey Lee, Nizar Mukhtar   +11 more
doaj   +1 more source