Results 51 to 60 of about 18,378,232 (237)

von Willebrand factor as a biomarker of clinically significant portal hypertension and severe portal hypertension: a systematic review and meta-analysis

BMJ Open, 2019
Objective This meta-analysis was performed to investigate the correlation between von Willebrand factor (vWF) antigen and hepatic venous pressure gradient (HVPG) and to evaluate the diagnostic performance of vWF to detect clinically significant portal ...
Chunqing Zhang, Ziyuan Zou, Xinwen Yan, Cheng Li, Xiaofeng Li, Xiaofen Ma, Shenghong Ju, Junzhang Tian, Xiaolong Qi   +8 more
doaj   +1 more source

NON-INVASIVE PREDICTORS OF PORTAL HYPERTENSION IN PATIENTS WITH HEPATITIS C VIRUS RELATED HEPATOCELLULAR CARCINOMA [PDF]

Journal of the Egyptian Society of Parasitology, 2015
The reference standard for portal venous pressure measurement which is clinically important for estimating the feasibility of resection of hepatocellular carcinoma is the hepatic venous pressure gradient, which is invasive and expensive.
MOHAMED ABOU-ELMAATY, MOHAMED ABD AL-HAMID, AHMED ELBAZ, EMAN BARAKAT, MOHAMED SAKR, ZAKARIA MOHRAN   +5 more
doaj   +1 more source

LIVER ABLATION IN CIRRHOTIC PATIENTS WITH CLINICALLY SIGNIFICANT PORTAL HYPERTENSION: CURRENT EVIDENCE, CHALLENGES, AND EMERGING ROLE OF ELASTOGRAPHY

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale
Liver ablation is a cornerstone therapy for early-stage hepatocellular carcinoma (HCC), offering a curative-intent option for patients ineligible for resection or transplantation. However, the presence of clinically significant portal hypertension (CSPH)
Angela PELTEC, Artur BODRUG, Inga BODRUG, Roman BODRUG   +3 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: The "Anticipate" study. [PDF]

, 2016
In patients with compensated advanced chronic liver disease (cACLD), the presence of clinically significant portal hypertension (CSPH) and varices needing treatment (VNT) bears prognostic and therapeutic implications.
Annalisa Berzigotti, Blasco, Hélène, Salvador Augustin, Christophe Bureau, Stefanescu, Horia, Procopet, Bogdan, Juan G. Abraldes, Hélène Blasco, Augustin, Salvador, Berzigotti, Annalisa, Jaime Bosch, Bureau, Christophe, Horia Stefanescu, Genesca, Joan, Michael Ney, Joan Genesca, Abraldes, Juan G, Bosch, Jaime, Ney, Michael, Bogdan Procopet   +19 more
core   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Variability of transient elastography-based spleen stiffness performed at 100 Hz

European Radiology Experimental, 2023
Background Spleen stiffness measurement (SSM) performed by transient elastography at 100 Hz is a novel technology for the evaluation of portal hypertension in advanced chronic liver disease, but technical aspects are lacking.
Angelo Armandi, Talal Merizian, Merle Marie Werner, Harvey O. Coxson, Tiziana Sanavia, Giovanni Birolo, Isabella Gashaw, Judith Ertle, Maurice Michel, Peter R. Galle, Christian Labenz, Tilman Emrich, Jörn M. Schattenberg   +12 more
doaj   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America

JGH Open, 2022
Background and Aim Obliterative portal venopathy (OPV) is one of the causes of non‐cirrhotic portal hypertension. However, many aspects of OPV remain unclear, including the etiology, pathogenesis, and natural history.
Vinícius Nunes, Luiz A R deFreitas, Juliana R deFreitas, Caio Araújo, Gildásio N Junior, Maria I Schinoni, Fernando Bessone, Raymundo Paraná   +7 more
doaj   +1 more source

Portal Hypertension among Patients with Chronic Liver Disease Admitted to the Department of Internal Medicine of a Tertiary Care Centre

Journal of Nepal Medical Association, 2023
Introduction: Portal hypertension is increased pressure within the portal vein. A portal pressure gradient of more than 10 mmHg is defined as "clinically significant portal hypertension" due to manifestations such as splenomegaly, gastroesophageal ...
Sabina Khadka, Ananda Aryal, Sagun Karki, Pratik Subedi, Kanchan Bogati, Sunil Baniya, Shrekshya Khadka, Kumar Roka, Asha Shahi   +8 more
doaj   +1 more source