Results 91 to 100 of about 3,979 (194)

Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model

Neurobiology of Disease, 2013
The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, on multiple sclerosis pathogenesis. Experimental autoimmune encephalomyelitis was induced by immunization with myelin oligodendrocyte glycoprotein (MOG(35–
Bo Young Choi, Bong Geom Jang, Jin Hee Kim, Jae-Nam Seo, Guang Wu, Min Sohn, Tae Nyoung Chung, Sang Won Suh   +7 more
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Prevention of Travelers' Diarrhea by Nonantibiotic Drugs [PDF]

, 2017
Travelers have resorted to a variety of drugs for prevention of diarrhea. No beneficial prophylactic effect has been confirmed for halogenated hydroxyquinolines, lactobacilli, antimotility drugs, ethacridine, and various other agents.
DuPont, Herbert L., Heusser, Rolf, Steffen, Robert   +2 more
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Interventions for skin changes caused by nerve damage in leprosy

São Paulo Medical Journal
BACKGROUND More than three million persons are disabled by leprosy worldwide. The main complication of sensory nerve damage is neuropathic ulceration, particularly of the feet. In this review we explored interventions that can prevent and treat secondary
Liv Merete Reinar, Louise Forsetlund, Arild Bjrndal, Diana Lockwood   +3 more
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Intra-antral application of an anti-fungal agent for recurrent maxillary fungal rhinosinusitis: a case report

Journal of Medical Case Reports, 2012
Introduction Fungal infection of the paranasal sinuses is an increasingly recognized entity both in immunocompetent and immunocompromised individuals. Treatment has been via use of either surgical or medical modalities, or a combination of the two. Here,
Dunmade Adekunle D, Afolabi Olushola A, Alabi Biodun S, Segun-Busari Segun, Koledoye Olubisi A   +4 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Two hydroxy pyridinecarboxylic acid derivatives as a possible chelating agents in neurodegenerative disease; equilibrium complexation studies with Cu(II), Zn(II). [PDF]

, 2014
The metal ion chelators 4-hydroxy-5-methyl-3-pyridinecarboxylic acid (DQ5) and 1,5-dimethyl-4-hydroxy-3-pyridinecarboxylic acid (DQ715) and Cu(II) and Zn(II) were investigated with the aim to restore the homeostasis of the brain Cu(II) and Zn(II) in ...
Dean, Annalisa, Di Marco, Valerio B., Gandin, Valentina, Jakusch, Tamás, Kiss, Tamás, Marzano, Christine, Nagy, Nóra Veronika, Sija, Éva   +7 more
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Nanodrug‐Engineered Exosomes Achieve a Jointly Dual‐Pathway Inhibition on Cuproptosis

Advanced Science
Cuproptosis, caused by an intracellular overload of copper (Cu) ions and overexpression of ferredoxin 1 (FDX1), is identified for its regulatory role in the skin wound healing process.
Hanxiao Sun, Yang Zou, Zhengtai Chen, Yan He, Kai Ye, Huan Liu, Lihong Qiu, Yufan Zhang, Yuexue Mai, Xinghong Chen, Zhengwei Mao, Wei Wang, Chenggang Yi   +12 more
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QM, Fukui function, molecular docking, molecular dynamics investigation on Human Estrogen Receptor (HER) with Clioquinol

Chemical Physics Impact
Clioquinol is an antifungal medication that is used to treat skin diseases such as dermatitis, foot inflammation, sports itch, and ringworm The electron localization and delocalization indices in position space are further quantum chemical instruments ...
Chandramohan Uma Maheswari
doaj   +1 more source

Chelators in Iron and Copper Toxicity [PDF]

Purpose of Review Chelation therapy is used for diseases causing an imbalance of iron levels (for example haemochromatosis and thalassaemia) or copper levels (for example Menkes’ and Wilson’s diseases).
A Hartwig, A Kattamis, A Miyashiro, AC Dlouhy, AV Hoffbrand, B Gupta, BE Holbein, BE Kim, BM Olabinri, C Thephinlap, CG Roussaeux, CL Alden, CW Ritchie, DJ Kosman, DM Seely, DS Kalinowski, DW Cox, ED Rosenstein, G Lewis, GE Cartwright, GJ Brewer, HV Aposian, IS MacPherson, J Aaseth, J Aaseth, JH Menkes, JM Walshe, JM Walshe, K Aayush, K Brzóska, K Grasedyck, K Jomova, KA Winship, L Alan, L Lannfelt, M Nairz, MD Cappellini, MG Thompson, ML Schilsky, P Das, P Delangle, PJ Crouch, PJ Giardina, RL Anderson, RM Robins-Browne, RR Crichton, S Srichairatanakool, S Waldvogel-Abramowskia, SJS Flora, SK Das, SR Bareggi, T Umemura, TA Rouault, TD Rae, TP Kennedy, U Merle, V Laufberger, V Oliveri, Y Hiasa   +58 more
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Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells

Drug Design, Development and Therapy, 2015
Waraporn Chan-on,1 Nguyen Thi Bich Huyen,2 Napat Songtawee,3 Wilasinee Suwanjang,1 Supaluk Prachayasittikul,3 Virapong Prachayasittikul2 1Center for Research and Innovation, 2Department of Clinical Microbiology and Applied Technology, 3Center of Data ...
Chan-on W, Huyen NTB, Songtawee N, Suwanjang W, Prachayasittikul S, Prachayasittikul V   +5 more
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