Results 91 to 100 of about 88,264 (269)

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

PB1936: IDENTIFYING INEQUITIES IN SUPPORT - GLOBAL SURVEY OF PATIENT ORGANISATIONS DELIVERING SUPPORT SERVICES FOR CLL PATIENTS

HemaSphere, 2023
Deborah Baker, Nick York, Kathryn Huntley, Michael Rynne, Nicole Schroeter, Pierre Aumont, Brian Koffman, Felice Bombaci, Jennie Bradley, Lynsey Fenwick, Anna Schuh, Alina S. Gerrie, Norah O. Akinola, Yervand Hakobyan, Nicole Lamanna, Versha Banerji, Renata Walewska, Paolo Ghia   +17 more
doaj   +1 more source

sj-jpg-4-cll-10.1177_09636897231198178 – Supplemental material for Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia

, 2023
Supplemental material, sj-jpg-4-cll-10.1177_09636897231198178 for Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia by Uday Kulkarni, Arun Kumar Arunachalam, Hamenth ...
Arun Kumar Arunachalam (16630276), Reeshma Radhakrishnan Nair (16987478), Anu Korula (5392655), Nithya Balasundaram (3580517), Uday Kulkarni (16987475), Arvind Venkatraman (16987481), Sushil Selvarajan (16987484), Biju George (407764), Hamenth Kumar Palani (5392667), Vikram Mathews (407763), Sharon Lionel (16987487), Aby Abraham (407766), Poonkuzhali Balasubramanian (714388), Madhavi Maddali (16987490)   +13 more
core   +1 more source

Sustainability in Business Process Management: Research Landscape and Theoretical Implications

Sustainable Development, EarlyView.
ABSTRACT Sustainability in Business Process Management (BPM) is a growing priority for organisations seeking to balance operational efficiency with environmental and social responsibility. Although research highlights the benefits of integrating sustainability into BPM—such as regulatory compliance, cost reduction and corporate reputation enhancement ...
Silvia Dallavalle, João Henrique Paulino Pires Eustachio, Walter Leal Filho, Maria Laura Salomão David, Alexandre Rodrigues Cajuela, Lara Letícia Donegá Carreira   +5 more
wiley   +1 more source

PB2673: EXPERIENCES AND VIEWS OF LEUKEMIA CARERS: A GLOBAL SURVEY

HemaSphere, 2023
Samantha Nier, Zack Pemberton-Whiteley, Nick York, Kathryn Huntley, Deborah Baker, Michael Rynne, Nicole Schroeter, Denis Costello, Lidija Pecova, Esther Natalie Oliva, Tatyana Ionova, Sam Salek   +11 more
doaj   +1 more source

Linking SLAMF1 to autophagy and sensitivity to therapy in chronic lymphocytic leukemia

Molecular & Cellular Oncology, 2018
We recently reported that expression of the costimulatory molecule and microbial sensor SLAMF1 (signaling lymphocytic activation molecule family 1, also known as CD150) is lost in chronic lymphocytic leukemia (CLL) patients characterized by a shorter ...
Cinzia Bologna, Silvia Deaglio
doaj   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

sj-docx-1-cll-10.1177_09636897221108705 – Supplemental material for Cooling of Cells and Organs Confers Extensive DNA Strand Breaks Through Oxidative Stress and ATP Depletion

, 2022
Supplemental material, sj-docx-1-cll-10.1177_09636897221108705 for Cooling of Cells and Organs Confers Extensive DNA Strand Breaks Through Oxidative Stress and ATP Depletion by Marziyeh Tolouee, Koen D. W. Hendriks, Fia Fia Lie, Lucas P.
Koen D. W. Hendriks (7887083), Femke Hoogstra-Berends (217817), Maaike Goris (550181), Steven Bergink (13024636), Fia Fia Lie (13024630), Marziyeh Tolouee (13024627), Robert H. Henning (11182560), Lucas P. Gartzke (13024633)   +7 more
core   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab

Hematology/Oncology and Stem Cell Therapy, 2017
Objective/background: Membranoproliferative glomerulonephritis (MPGN) is a common extramedullary renal presentation in chronic lymphocytic leukemia (CLL) and can present with either a frank renal failure or proteinuria.
Punit Jain, Rashmi Kanagal-Shamanna, William Wierda, Alessandra Ferrajoli, Michael Keating, Nitin Jain   +5 more
doaj   +1 more source