Results 41 to 50 of about 88,264 (269)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Anisotropic Memristive Switching in NbOCl2 Enabled by Directional Oxygen Ion Migration

Advanced Science, EarlyView.
This study investigates strongly orientation‐dependent memristive switching in anisotropic NbOCl2, observed exclusively along the in‐plane c‐axis. The switching originates from direction‐selective oxygen‐ion migration and vacancy propagation that modulate the Pd/NbOCl2 Schottky barrier, enabling short‐term plasticity.
Caokun Wang, Yun Ji, Sanchali Mitra, Yufei Shi, Haofei Zheng, Yee Sin Ang, Kah‐Wee Ang   +6 more
wiley   +1 more source

Obinutuzumab activates FcγRI more potently than other anti-CD20 antibodies in chronic lymphocytic leukemia (CLL)

OncoImmunology, 2018
Treatment with monoclonal antibodies has revolutionized clinical medicine, especially in the fields of cancer and immunology. One of the oldest antibodies, which is widely used for the treatment of lymphomas and autoimmune diseases, is the anti-CD20 ...
Shlomo Elias, Shira Kahlon, Rebecca Kotzur, Noah Kaynan, Ofer Mandelboim   +4 more
doaj   +1 more source

COVID-19 and fortuitous discovery of chronic lymphocytic leukemia: biological findings and therapeutic challenges

The Pan African Medical Journal, 2020
With the major spread of SARS-COV-2 around the world, its association with various pathologies has been reported. However, hemopathy has rarely been revealed during a coronavirus infection.
Boubaker Charra, Ayman Ellouadghiri, Abdellah Magramane, Touda Kebbou, Kenza Damaan, Abdeljabbar Maghfour, Kamal Seddiki, Hanane Ezzouine   +7 more
doaj   +1 more source

sj-docx-1-cll-10.1177_09636897231198178 – Supplemental material for Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia

, 2023
Supplemental material, sj-docx-1-cll-10.1177_09636897231198178 for Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia by Uday Kulkarni, Arun Kumar Arunachalam, Hamenth ...
Arun Kumar Arunachalam (16630276), Reeshma Radhakrishnan Nair (16987478), Anu Korula (5392655), Nithya Balasundaram (3580517), Uday Kulkarni (16987475), Arvind Venkatraman (16987481), Sushil Selvarajan (16987484), Biju George (407764), Hamenth Kumar Palani (5392667), Vikram Mathews (407763), Sharon Lionel (16987487), Aby Abraham (407766), Poonkuzhali Balasubramanian (714388), Madhavi Maddali (16987490)   +13 more
core   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Disease-specific complications of chronic lymphocytic leukemia in binet stage a patients [PDF]

, 2012
Disease-specific Complications of Chronic Lymphocytic Leukemia in Binet Stage A Patients: Analysis of Immunodeficiency, Autoimmune Constellations and Infections in the CLL1-Protocol.
Kwag, Doo Young
core   +1 more source

sj-tif-2-cll-10.1177_09636897221084354 – Supplemental material for A Robust and Highly Efficient Approach for Isolation of Mesenchymal Stem Cells From Wharton’s Jelly for Tissue Repair

, 2022
Supplemental material, sj-tif-2-cll-10.1177_09636897221084354 for A Robust and Highly Efficient Approach for Isolation of Mesenchymal Stem Cells From Wharton’s Jelly for Tissue Repair by Shengxia Zheng, Yanyan Gao, Kai Chen, Yusheng Liu, Ninuo Xia and ...
Shengxia Zheng (10312748), Fang Fang (38179), Ninuo Xia (12281237), Yusheng Liu (1285077), Yanyan Gao (2986050), Kai Chen (129938)   +5 more
core   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

sj-docx-2-cll-10.1177_09636897221133345 – Supplemental material for Intrauterine Injection of Umbilical Cord Mesenchymal Stem Cell Exosome Gel Significantly Improves the Pregnancy Rate in Thin Endometrium Rats

, 2022
Supplemental material, sj-docx-2-cll-10.1177_09636897221133345 for Intrauterine Injection of Umbilical Cord Mesenchymal Stem Cell Exosome Gel Significantly Improves the Pregnancy Rate in Thin Endometrium Rats by Shengning Zhang, Dongmei Wang, Fang Yang ...
Yanjun Shen (389969), Dongmei Wang (282313), Fang Yang (123514), Shengning Zhang (14054863), Dong Li (212687), Xiaohui Deng (534130)   +5 more
core   +1 more source