Postnatal ontogenesis of clock genes in mouse suprachiasmatic nucleus and heart [PDF]
Lipids in Health and Disease, 2010 Background The master clock within the hypothalamic suprachiasmatic nucleus (SCN) synchronizing clocks in peripheral tissues is entrained by the environmental condition, such as the light-dark (LD) cycle. The mechanisms of circadian clockwork are similar
Hua Luchun +4 more
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Phylogenetic footprint of the plant clock system in angiosperms: evolutionary processes of
BMC Evolutionary Biology, 2010 Background Plant circadian clocks regulate many photoperiodic and diurnal responses that are conserved among plant species. The plant circadian clock system has been uncovered in the model plant, Arabidopsis thaliana, using genetics and systems biology ...
Saito Shigeru +3 more
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The nuclear receptor genes HR3 and E75 are required for the circadian rhythm in a primitive insect. [PDF]
PLoS ONE, 2014 Insect circadian rhythms are generated by a circadian clock consisting of transcriptional/translational feedback loops, in which CYCLE and CLOCK are the key elements in activating the transcription of various clock genes such as timeless (tim) and period
Yuichi Kamae +3 more
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Altered circadian expression of clock genes and clock-regulatory epigenetic modifiers in saliva of children with fetal alcohol spectrum disorders [PDF]
Scientific ReportsPrenatal alcohol-exposed (AE) infants and children often demonstrate disrupted sleep patterns, including more frequent awakenings, reduced total sleep time, and more night-to-night sleep variability.
Ujjal Das +6 more
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Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]
, 2015 The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Farjo, Bessam +4 more
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Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain
Frontiers in Physiology, 2021 To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1).
Charlotte M. Bolton +4 more
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A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response. [PDF]
PLoS ONE, 2012 Circadian rhythm abnormalities in bipolar disorder (BD) have led to a search for genetic abnormalities in circadian "clock genes" associated with BD. However, no significant clock gene findings have emerged from genome-wide association studies (GWAS). At
Michael J McCarthy +3 more
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Cells, 2021 The circadian clock drives time-specific gene expression, enabling biological processes to be temporally controlled. Plants that conduct crassulacean acid metabolism (CAM) photosynthesis represent an interesting case of circadian regulation of gene ...
Robert C. Moseley +4 more
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Feeding period restriction alters the expression of peripheral circadian rhythm genes without changing body weight in mice. [PDF]
PLoS ONE, 2012 Accumulating evidence suggests that the circadian clock is closely associated with metabolic regulation. However, whether an impaired circadian clock is a direct cause of metabolic dysregulation such as body weight gain is not clearly understood. In this
Hagoon Jang +5 more
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Ensemble Methods for Identifying RNA Operons and Regulons in the Clock Network of Neurospora Crassa
IEEE Access, 2022 With both light entrainment data (L/D) and free running data in the dark (D/D), Variable Topology Ensemble Methods (VTENS) were used to reconstruct the entire genome-scale clock network involving 3380 genes and their products under the hypothesis that ...
Ahmad M. Al-Omari +5 more
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