Results 171 to 180 of about 157,763 (284)

Association between dietary intake and the expression of clock genes in adults: a brief report. [PDF]

Front Nutr
Lages M, Barros R, Ferreira-Marques M, Correia J, Caseiro A, Guarino MP, Carmo-Silva S.   +6 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Melatonin modulates the gene expression of WEE1 kinase and clock genes: a crosstalk between the molecular clocks of the placenta? [PDF]

Front Endocrinol (Lausanne)
Venegas C, Jara-Medina K, Cueto N, Cabello-Guzmán G, Lagunas C, Lillo L, Valenzuela-Melgarejo FJ.   +6 more
europepmc   +1 more source

Clock gene

Journal of the Illuminating Engineering Institute of Japan, 1999
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Progress in understanding how clock genes regulate aging and associated metabolic processes. [PDF]

Front Physiol
Su Y, Wang M, Chen J, Bao Y, Wen R, Ren HW, Luan ZL.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Circadian Rhythms and Pain: A Narrative Review on Clock Genes and Circadian-Based Interventions. [PDF]

J Pain Res
Huang ZQ, Li XQ, Wang YD, Li JY, Tian YH, Liu YM, Si JQ.   +6 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Prenatal alcohol exposure dysregulates the expression of clock genes and alters rhythmic behaviour in mice. [PDF]

Open Biol
Reina-Campos M, Gallego-Landin I, Medrano M, Garcia-Baos A, Valverde O.   +4 more
europepmc   +1 more source