Results 41 to 50 of about 157,763 (284)

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. [PDF]

, 2013
The p75 neurotrophin receptor (p75(NTR)) is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle.
Akassoglou, Katerina, Baeza-Raja, Bernat, Eckel-Mahan, Kristin, Ptácek, Louis J, Sassone-Corsi, Paolo, Tsigelny, Igor F, Vagena, Eirini, Zhang, Luoying   +7 more
core   +2 more sources

P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation

Journal of Circadian Rhythms, 2018
In mammals, circadian rhythmicity is sustained via a transcriptional/translational feedback loop referred to as the canonical molecular circadian clock.
Abdullah Mashhour, Zainab Al Mansour, Al Shaima Al Hallaj, Rizwan Ali, Thadeo Trivilegio, Mohamed Boudjelal   +5 more
doaj   +1 more source

Circadian clocks and breast cancer [PDF]

, 2016
Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V, Meng, Q-J, Streuli, CH, Williams, JL   +3 more
core   +2 more sources

Human clock genes

Annals of Medicine, 2002
Rhythmic variations in physiological and behavioural processes are mediated by both endogenous and exogenous factors. Endogenous factors include self-sustaining biological pacemakers or clocks which in the absence of strong external influences self-sustain periodic rhythms in such diverse physiological and psychological processes as core body ...
openaire   +2 more sources

Daily rhythmicity of clock gene transcripts in atlantic cod fast skeletal muscle. [PDF]

PLoS ONE, 2014
The classical notion of a centralized clock that governs circadian rhythmicity has been challenged with the discovery of peripheral oscillators that enable organisms to cope with daily changes in their environment. The present study aimed to identify the
Carlo C Lazado, Hiruni P S Kumaratunga, Kazue Nagasawa, Igor Babiak, Alessia Giannetto, Jorge M O Fernandes   +5 more
doaj   +1 more source

Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis [PDF]

, 2018
BACKGROUND: Dysfunction of the circadian clock and polymorphisms of some circadian genes have been linked to cancer development and progression. We investigated the relationship between circadian genes germline variation and susceptibility or prognosis ...
Benna, Clara, Del Fiore, Paolo, Mocellin, Simone, Rajendran, Senthilkumar, Rossi, Carlo Riccardo, Spiro, Giovanna, Tropea, Saveria   +6 more
core   +2 more sources

Circadian clock disruption in autoimmune thyroiditis

European Thyroid Journal, 2023
Objective: A vicious cycle between circadian disruption and escalating immune responses has been described in diverse inflammatory disease. The current study aimed to explore the role of circadian clock disruption in autoimmune thyroiditi s (AIT ...
Jinrong Fu, Zihao Fan, Liang He, Qian Liu, He Liu, Yushu Li, Haixia Guan   +6 more
doaj   +1 more source

Molecular mechanisms in mood regulation involving the circadian clock [PDF]

, 2017
The circadian system coordinates activities and functions in cells and tissues in order to optimize body functions in anticipation to daily changes in the environment.
Albrecht, Urs
core   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin   +9 more
wiley   +1 more source

Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

Lipids in Health and Disease, 2017
Background The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic plaque formation and rupture.
Changpo Lin, Xiao Tang, Lirong Xu, Ruizhe Qian, Zhenyu Shi, Lixin Wang, Tingting Cai, Dong Yan, Weiguo Fu, Daqiao Guo   +9 more
doaj   +1 more source