Results 181 to 190 of about 127,418 (322)

Multiple random phosphorylations in clock proteins provide long delays and switches. [PDF]

Sci Rep, 2020
Upadhyay A, Marzoll D, Diernfellner A, Brunner M, Herzel H.   +4 more
europepmc   +1 more source

Alternative Initiation of Translation and Time-Specific Phosphorylation Yield Multiple Forms of the Essential Clock Protein FREQUENCY [PDF]

, 1997
Norman Garceau, Yi Liu, Jennifer Loros, Jay Dunlap   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Non-cyclic and Developmental Stage-Specific Expression of Circadian Clock Proteins During Murine Spermatogenesis1 [PDF]

, 2003
John Alvarez, Dechun Chen, E Storer, Amita Sehgal   +3 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

When lowering temperature, the in vivo circadian clock in cyanobacteria follows and surpasses the in vitro protein clock trough the Hopf bifurcation [PDF]

I. Mihalcescu, Hotaka Kaji, H Maruyama, J.P. Giraud, Mathilde Van Melle-Gateau, Bahram Houchmandzadeh, Hiroshi Ito   +6 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Faculty Opinions recommendation of Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila.

, 2006
Louis J. Ptáček
openalex   +2 more sources

Robust circadian clocks from coupled protein-modification and transcription–translation cycles [PDF]

, 2010
David Zwicker, David K. Lubensky, Pieter Rein ten Wolde   +2 more
openalex   +1 more source

Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythm and sleep [PDF]

, 2023
Yuanqiang Sun, Ke Shui, Qinyu Li, Chenlu Liu, Wanting Jin, Jian‐Quan Ni, Jian Lü, Luoying Zhang   +7 more
openalex   +1 more source