Results 251 to 260 of about 125,163 (295)

Mechanism and reconstitution of circadian transcription in cyanobacteria. [PDF]

open access: yesNat Struct Mol Biol
Fang M   +7 more
europepmc   +1 more source

Clock regulation of protein secretion

Nature Cell Biology, 2020
The molecular clock regulates the rhythmic transcription of myriad genes, leading to a circadian pattern of expression of the encoded proteins. A study demonstrates circadian regulation of expression of components of the protein secretory pathway, providing a mechanism to generate circadian patterns of secreted protein expression.
openaire   +2 more sources

Determining Divergence Times With Protein Clocks

The Biological Bulletin, 1999
ported was a divergence time for prokaryotes and eukaryotes of only slightly more than two billion years ago. In line with this result, the average resemblance of these enzymes between Bacteria (a.k.a. eubacteria) and Eukarya (a.k.a. eukaryotes) was 37% identity.
R F, Doolittle, D F, Feng, G, Cho
openaire   +2 more sources

Chromatin Immunoprecipitation Protocol for Circadian Clock Proteins

2021
Chromatin immunoprecipitation, or ChIP, is a powerful experimental technique for probing protein-DNA interactions in vivo. This assay can be used to investigate the association of a protein of interest with specific target loci. Alternatively, it can be combined with high-throughput sequencing technology to identify genome-wide binding sites.
Sally, Adams, Isabelle A, Carré
openaire   +2 more sources

Nucleic acid and protein clocks

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1991
The use of pairwise comparisons of correctly aligned DNA and protein sequences for the measurement of time in historical biology remains a contentious matter. However, the limited success of some molecular evolutionary clocks provides a stimulus to attempt to improve their resolution by the judicious selection of sequences for ease of alignment ...
openaire   +2 more sources

Holins: The Protein Clocks of Bacteriophage Infections

Annual Review of Microbiology, 2000
▪ Abstract  Two proteins, an endolysin and a holin, are essential for host lysis by bacteriophage. Endolysin is the term for muralytic enzymes that degrade the cell wall; endolysins accumulate in the cytosol fully folded during the vegetative cycle. Holins are small membrane proteins that accumulate in the membrane until, at a specific time that is ...
I N, Wang, D L, Smith, R, Young
openaire   +2 more sources

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