Results 51 to 60 of about 8,788 (204)

Therapie des Xanthoma disseminatum – eine systematische Literaturrecherche

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 9, Page 1061-1070, September 2025.
Zusammenfassung Das Xanthoma disseminatum ist eine seltene Erkrankung aus dem Spektrum der Nicht‐Langerhans‐Zell‐Histiozytosen, welche in drei Gruppen eingeteilt werden kann und teilweise mit einer Systembeteiligung einhergeht. Da die Erkrankung selten ist, fehlen standardisierte Therapierichtlinien, wodurch die Behandlung im klinischen Alltag ...
Inga Hansen‐Abeck, Mina Hillemans, Finn Abeck, Stefan W. Schneider, Nina Booken   +4 more
wiley   +1 more source

Deciphering the panvascular immune landscape of atherosclerosis

VIEW, Volume 6, Issue 4, August 2025.
Atherosclerosis (AS) involves inflammation in major arteries and can cause severe cardiovascular events like heart attacks and strokes, yet disease patterns vary significantly between arteries, complicating diagnosis and treatment. In this study, we integrated transcriptomic and single‐cell RNA sequencing data from AS plaques across five key arterial ...
Yiming Zhong, Yifan Chen, Yuehong Wang, Wenhai Pan, Honghao Huang, Lin Lin Cao, Yili Wang, Jiawen Zhang, Yunyi Liang, Xiangyue Qian, Chenxi Shi, Xiyuan Lu, Jun Pu   +12 more
wiley   +1 more source

Clinical Pharmacology in the UK, c.1950-2000: Industry and Regulation [PDF]

, 2008
Annotated and edited transcript of a Witness Seminar held on 25 September 2007. Introduction by Professor Parveen Kumar, Barts and the London School of Medicine and Dentistry, University of London.First published by the Wellcome Trust Centre for the ...
Reynolds, LA, Tansey, EM
core  

Genes involved in carnitine synthesis and carnitine uptake are up-regulated in the liver of sows during lactation [PDF]

, 2013
BACKGROUND:Convincing evidence exist that carnitine synthesis and uptake of carnitine into cells is regulated by peroxisome proliferator-activated receptor alpha (PPARA), a transcription factor which is physiologically activated during fasting or energy ...
Becker, Sabrina, Eder, Klaus, Erhardt, Georg, Hillen, Sonja, Most, Erika, Reiner, Gerald, Ringseis, Robert, Rosenbaum, Susann   +7 more
core   +2 more sources

Clofibrate-Induced Antidiuresis [PDF]

Journal of Clinical Investigation, 1973
Normal subjects and patients with antidiuretic hormone (ADH) deficiency were studied to determine the mechanism of the antidiuretic action of clofibrate. Before clofibrate treatment, the patients' ability to concentrate urine with a standardized dehydration procedure correlated with the amount of ADH which was excreted. During clofibrate administration
A M, Moses, J, Howanitz, M, van Gemert, M, Miller   +3 more
openaire   +2 more sources

Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5‐Mediated Myocardial Inflammation

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Cardiomyocyte‐specific overexpression of ERRγ after myocardial infarction improves cardiac function by suppressing the expression of its pro‐inflammatory downstream target GBP5, thereby inhibiting inflammasome assembly, alleviating myocardial inflammation, and pyroptosis.
Junhao Qiu, Qianji Che, Yichao Zhang, Mu Chen, Zhixing Wei, Yangjinming Bai, Tingting Zhao, Ji Yan, Zhengyang Wu, Zhentao Fei, Yuepeng Wang, Qian Wang, Yi‐Gang Li   +12 more
wiley   +1 more source

Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) [PDF]

, 2010
10.1186/1471-2164-11-16BMC Genomics111 ...
Beena Vallanat, Steven P Anderson, Holly M Brown-Borg, Hongzu Ren, Sander Kersten, Sudhakar Jonnalagadda, Rajagopalan Srinivasan, J Christopher Corton   +7 more
core   +2 more sources

Optimized Dynamic Network Biomarker Deciphers a High‐Resolution Heterogeneity Within Thyroid Cancer Molecular Subtypes

Med Research, Volume 1, Issue 1, Page 10-31, June 2025.
An optimized dynamic network biomarker approach reveals a critical transition signal and identifies three distinct molecular subtypes of differentiated thyroid cancer, each with unique global regulatory landscapes. ABSTRACT The progression of differentiated thyroid carcinoma (DTC) poses significant clinical challenges, especially in determining the ...
Haonan Zhang, Ge Zhang, Pengyuan Xu, Fengyi Yu, Liwen Li, Runzhi Huang, Pengpeng Zhang, Kaisaierjiang Kadier, Yuanyuan Wang, Qiqi Gu, Yalei Ding, Tianshu Gu, Hao Chi, Shiqian Zhang, Ruhao Wu, Yudi Xu, Shanshan Zhu, Honglin Zheng, Taiqi Zhao, Qi He, Xinguang Qiu   +20 more
wiley   +1 more source

The Effect of Clofibrate on Hyperbilirubinemia of Term Neonates [PDF]

Acta Medica Iranica, 2012
Clofibrate is a glucuronosyl transferase inducer that has been proposed to increase the elimination of bilirubin in neonates with hyperbilirubinemia. This study was conducted to determine the therapeutic effect of clofibrate in term neonates with non ...
Morteza Habibi, Abolfazl Mahyar, Parviz Ayazi, Farzad Ahmadabadi, Amir Javadi   +4 more
doaj   +1 more source

Iatrogenia a importância do diagnóstico clínico miopatia induzida por clofibrate

Arquivos de Neuro-Psiquiatria, 1992
Os autores descrevem o caso de uma enferma que apresentou síndrome polimio-site símile durante tratamento de hipercolesterolemia com clofibrate. Com ia suspensão da medicação, os sinais e sintomas de acometimento muscular desapareceram por completo.
J. M. Godoy, Denise H. Nicaretta, S. L. Balassiano, M. Skacel   +3 more
doaj   +1 more source