Results 41 to 50 of about 4,936 (166)

Use of Clofibrate to Bypass Nuclear Targeting in the Development of Non-Viral Gene Delivery Systems

open access: yes, 2019
Clofibrate is a commercially available chemical that has been found to induce increased cell division in the hepatocytes of rodents. Previous experiments in our lab have investigated the use of clofibrate to bypass the need for nuclear targeting in non ...
Blocklinger, Kelsey
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THE TOXIC EFFECTS OF CLOFIBRATE AND ITS METABOLITE ON MAMMALIAN SKELETAL MUSCLE: AN ELECTROPHYSIOLOGICAL STUDY

open access: yes, 1984
Membrane electrical parameters of rat extensor digitorum longus muscles were analysed in vitro, with intracellular microelectrodes, after chronic treatment with clofibrate or after in vitro application of chlorophenoxyisobutyric acid, the in vivo ...
TORTORELLA V   +3 more
core  

TISSUE-SPECIFIC DIFFERENTIAL INDUCTION OF DUPLICATED FATTY ACID-BINDING PROTEIN GENES BY THE PEROXISOME PROLIFERATOR, CLOFIBRATE, IN ZEBRAFISH (Danio rerio)

open access: yes, 2013
Duplicated genes are present in the teleost fish lineage owing to a whole-genome duplication (WGD) event that occured ~ 230-400 million years ago.
Venkatachalam, Ananda
core  

Evaluation of the Effect of Oral Clofibrate Intake on Neonatal Total Serum Bilirubin: a Randomized Clinical Trial

open access: yes, 2016
Background: Clofibrate is a pharmacological agent, which affects the lipid metabolism. This compound could be involved in bilirubin accumulation and excretion process.
Mahmood NouriShadkam   +2 more
core   +1 more source

Changes in desmin and vimentin contenst after clofibrate treatment on rats [PDF]

open access: yes, 2007
We analyzed in vivo effects of clofibrate and clofibric acid on vimentin and desmin content in rat myocardiocytes. Fifteen Sprague Dawley rats were divided in three groups of five animals each: clofibric acid, clofibrate, and untreated.
Cortés Gutiérrez, Elva Irene   +11 more
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The Effect of Clofibrate on Hyperbilirubinemia of Term Neonates

open access: yes, 2012
Clofibrate is a glucuronosyl transferase inducer that has been proposed to increase the elimination of bilirubin in neonates with hyperbilirubinemia. This study was conducted to determine the therapeutic effect of clofibrate in term neonates with non ...
Parviz Ayazi   +4 more
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Effects of Dietary Anaplerotic and Ketogenic Energy Sources on Renal Fatty Acid Oxidation Induced by Clofibrate in Suckling Neonatal Pigs

open access: yes, 2020
Maintaining an active fatty acid metabolism is important for renal growth, development, and health. We evaluated the effects of anaplerotic and ketogenic energy sources on fatty acid oxidation during stimulation with clofibrate, a pharmacologic ...
Yu Fan   +7 more
core   +1 more source

Preventive Effect of Clofibrate on Neonatal Hyperbilirubinemia

open access: yes, 2015
Background: Neonatal jaundice is a common problem that can result in serious neurological side effect such as Kern icterus. Several drugs are used to prevent neonatal jaundice.
Maryam Taheri   +4 more
core  

COMPARATIVE ULTRASTRUCTURAL EFFECTS OF CLOFIBRATE ON HUMAN (HEP EBNA2) AND RAT (FAO) HEPATOMA CELL LINES

open access: yes, 1995
Clofibrate and other structurally related compounds such as ciprofibrate. fenofibrate, nafenopin, are hyperlipoproteinemias. They effectively reduce plasma triglyceride and cholestrol levels and in many instances increase the level of plasma high ...
SCHOHN, H.   +3 more
core  

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