Results 81 to 90 of about 8,788 (204)
Clofibrate elevates enzyme activities of the tricarboxylic acid cycle in rat liver.
Activities of the tricarboxylic acid cycle enzymes were measured in subcellular fractions of liver from rats that had been fed clofibrate for 3 weeks. Large changes in these activities per gram tissue were found in the large particle fraction, which also
C Prager +6 more
doaj +1 more source
Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade [PDF]
Chagas disease is a significant health problem in Latin America and the available treatments have significant issues in terms of toxicity and efficacy.
Brough, Stephen J. +5 more
core +4 more sources
Key Articles, Guidelines, and Consensus Papers Relative to the Treatment of Dyslipidemias—2005 [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90074/1/phco.26.7.939 ...
Bianco, Theresa M. +6 more
core +1 more source
Hypolipidemic drugs increased 3- to 4-fold the activity of the peroxisomal beta-oxidation system in rat liver, with modest or no effects on catalase activity, liver weight, or peroxisome abundance.
P B Lazarow, H Shio, M A Leroy-Houyet
doaj +1 more source
Etiology and Management of Sexual Dysfunction [PDF]
Sexual dysfunction is the impairment or disruption of any of the three phases of normal sexual functioning, including loss of libido, impairment of physiological arousal and loss, delay or alteration of orgasm.
Bevinahalli Nanjegowda, Raveesh +5 more
core +2 more sources
PPARα Activation Protects against Anti-Thy1 Nephritis by Suppressing Glomerular NF-κB Signaling
The vast increase of chronic kidney disease (CKD) has attracted considerable attention worldwide, and the development of a novel therapeutic option against a representative kidney disease that leads to CKD, mesangial proliferative glomerulonephritis ...
Koji Hashimoto +7 more
doaj +1 more source
3Alpha, 7alpha, 12alpha-trihydroxy-5beta-cholestan-26-oic acid (C27-5beta-cholestanoic acid) derivatives with different carbon-number side chains were incubated with rat liver 800 g supernatant to study the effect of the side-chain length on the beta ...
T Kurosawa +4 more
doaj +1 more source
UPLC-MS/MS analysis of ochratoxin A metabolites produced by Caco-2 and HepG2 cells in a co-culture system [PDF]
Ochatoxin A (OTA) is one of the most important mycotoxins based on its toxicity. The oral route is the main gateway of entry of OTA into the human body, and specialized epithelial cells constitute the first barrier.
González Arias, Cyndia A. +4 more
core +2 more sources
Background Feeding oxidized fats causes activation of peroxisome proliferator-activated receptor α (PPARα) in the liver of rats. However, whether feeding oxidized fat during pregnancy also results in activation of PPARα in fetal liver is unknown.
Brandsch Corinna +4 more
doaj +1 more source
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters [PDF]
In order to investigate whether the stimulation of liver DNA synthesis might be used to detect one class of hepatic tumor promoters, the incorporation of orally administered radio-labelled thymidine into liver DNA was determined in rats and mice 24 h ...
Büsser, Marie-Therese, Lutz, Werner K.
core

