Results 141 to 150 of about 41,259 (301)

Inflammatory reprogramming of the solid tumor microenvironment by infiltrating clonal hematopoiesis is associated with adverse outcomes

Cell Reports Medicine
Summary: Clonal hematopoiesis (CH)—the expansion of somatically mutated hematopoietic cells—is common in solid cancers. CH is associated with systemic inflammation, but its impact on tumor biology is underexplored.
Marco M. Buttigieg, Caitlyn Vlasschaert, Alexander G. Bick, Robert J. Vanner, Michael J. Rauh   +4 more
doaj   +1 more source

Clonal Hematopoiesis

Journal of the American College of Cardiology, 2019
Peter Libby, Robert Sidlow, Amy E. Lin, Dipti Gupta, Lee W. Jones, Javid Moslehi, Andreas Zeiher, Siddhartha Jaiswal, Christian Schulz, Ron Blankstein, Kelly L. Bolton, David Steensma, Ross L. Levine, Benjamin L. Ebert   +13 more
openaire   +1 more source

Mature T‐cell leukemia/lymphoma with an NK‐like immunophenotype: A report of 7 cases

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Distinguishing T‐cell from NK‐cell neoplasms can occasionally be challenging, as neoplastic T cells can lose T‐cell markers such as surface CD3 (sCD3) and CD5 while acquiring NK‐cell markers such as CD16, CD56, and CD94. In this study, we present a series of 7 mature T‐cell lymphoma/leukemia cases with NK‐like immunophenotypes to clarify ...
Wei J. Wang, Sa A. Wang, Hong Fang, Jeffrey L. Jorgensen, Shimin Hu, Lianqun Qiu, Jie Xu, L. Jeffrey Medeiros, Wei Wang   +8 more
wiley   +1 more source

Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies [PDF]

, 2017
Allegra A. Petti, Amanda M. Smith, Angela M. Verdoni, Catrina Fronick, Celia V. Bangert, Christopher A. Miller, Christopher B. Cole, David A. Russler-Germain, Frith, Gue Su Chang, Jeffery M. Klco, Jeong, Mindy Guo, Nichole M. Helton, Poitras, Robert Fulton, Shamika Ketkar, Shelly O’Laughlin, Timothy J. Ley, Walter, Xi, Zheng   +21 more
core   +2 more sources

Results of chemotherapy by UKCCSG protocol in children with acute lymphoblastic leukemia: Clinical characteristics and outcome [PDF]

Background: Acute lymphoblastic leukemia (ALL) represents a clonal expansion and arrest of normal lymphoid hematopoiesis. ALL remains the most common malignancy in children.
فتحی, افشین, هیرادفر, امیر عطا ا..., پدرام, محمد   +2 more
core  

Clonal Hematopoiesis [PDF]

, 2020
openaire   +1 more source

Immunophenotypic characteristics of plasma cells in POEMS syndrome

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang, Tianling Ding, Beiqian Wu, Qiang Niu, Leyao Gu, Yan Yuan, Ping Zhu   +6 more
wiley   +1 more source

Clonal hematopoiesis in LGI1‐antibody encephalitis

Annals of Clinical and Translational Neurology
Objective Leucine‐rich glioma‐inactivated 1 (LGI1)‐antibody encephalitis (LGI1e), the major form of autoimmune encephalitis (AE) presented with memory loss and faciobrachial dystonic seizure, commonly develops in aged population.
Soo Jean Shin, Yoonhyuk Jang, Soo Hyun Ahn, Su Yee Mon, Ji Hye You, Hong Yul An, Choong Hyun Sun, Youngil Koh, Kon Chu, Sang Kun Lee, Soon‐Tae Lee   +10 more
doaj   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source