Results 151 to 160 of about 143,820 (254)

Minding the Gap: Follow-Up Cardiovascular Care After Clonal Hematopoiesis Detection. [PDF]

JACC Adv
Oren O, Singh A, Carraway HE, Menon V.
europepmc   +1 more source

Flow Cytometry‐Guided Diagnosis of Cortical T‐Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Chen Glait‐Santar, Yakir Moshe, Itzhaki‐Alfia Ayelet, Ben‐Zion Katz   +3 more
wiley   +1 more source

NETosis in the Kidney, Liver, and Lung of Mice With Cecal Ligation and Puncture‐Induced Sepsis and the Ameliorating Effects of Adipose‐Derived Stem Cell Exosomes

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced organ failure involves dysregulated neutrophil responses, including neutrophil extracellular trap (NET) formation, via NETosis. Exosomes generated from adipose‐derived stem cells (ADSCs) have shown potential in sepsis treatment. This study characterized organ‐specific NETosis in the kidney, liver, and lungs using a murine cecal ...
Shao‐Chun Wu, Tsu‐Hsiang Lu, Yi‐Chan Wu, Chia‐Wei Lin, Chia‐Wen Tsai, Ching‐Hua Hsieh   +5 more
wiley   +1 more source

Clonal Hematopoiesis in Colorectal Cancer: Mechanisms and Implications. [PDF]

Cancer Med
Xia C, Lu Y, Gu J.
europepmc   +1 more source

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado, Koustubh Bavdhankar, Divyani Garg, Francesca Magrinelli, Huw R. Morris, Kailash P. Bhatia   +5 more
wiley   +1 more source

DP016 | PREDICTING MYELOID NEOPLASMS IN CLONAL HEMATOPOIESIS: VALIDATION OF THE CHRS SCORE IN A POPULATION-BASED COHORT

Haematologica
The identification of premalignant conditions and their progression risks is a major focus in hematology. Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS)
A. Buizza, A. Campagna, M. Ubezio, G. Todisco, L. Lanino, A. Russo, G. Maggioni, C. Tentori, M. Zampini, F. Ficara, E. Riva, D. Ventura, N. Pinocchio, A. Crespi, I. Ferrari, G. Figini, M. Di Matteo, C. Delponte, A.A. Galbussera, M. Tettamanti, U. Lucca, M.G. Della Porta   +21 more
doaj  

Risk factors of clonal hematopoiesis of indeterminate potential. [PDF]

Clin Med (Lond)
Liu Q, Yang F, Adami HO, Zhao Y, Wästerlid T, Fang F, Liu Q.   +6 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Drivers of Inflammation; Clonal Hematopoiesis: Clinical Implications. [PDF]

Balkan Med J
Alp Kırkızlar T, Arat M.
europepmc   +1 more source