Results 121 to 130 of about 6,041 (204)

A non-conditioned bone marrow transplantation mouse model to study clonal hematopoiesis and myeloid malignancies

Experimental Hematology & Oncology
Clonal hematopoiesis of indeterminate potential (CHIP) is a condition where blood or bone marrow cells carry mutations associated with hematological malignancies.
Sofia Bentivegna, Marwa Almosailleakh, Lin-Pierre Zhao, Mikkel Bruhn Schuster, Sébastien Benquet, Alexander Balhuizen, Helga Fibiger Munch-Petersen, Lene Dissing Sjö, Mads Hald Andersen, Nicolas Dulphy, Bo Porse, Kirsten Grønbæk   +11 more
doaj   +1 more source

One Grammar, Many Labels: Revisiting the Continuum of Myeloid Neoplasms

Hematological Oncology, Volume 44, Issue 3, May 2026.
Francesco Tarantini, Cosimo Cumbo, Luisa Anelli, Antonella Zagaria, Nicoletta Coccaro, Angela Minervini, Giuseppina Tota, Elisa Parciante, Immacolata Redavid, Maria Rosa Conserva, Crescenzio Francesco Minervini, Angelo Cellamare, Paola Casieri, Maria Cristina Nuzzi, Paola Caforio, Alessandra Ricco, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +18 more
wiley   +1 more source

The CHIP-clinic as the catalyst of preventive medicine [PDF]

Clonal Hematopoiesis of Indeterminate Potential (CHIP) is associated with an increased risk of cardiovascular diseases (CVD) and is a precursor stage to the BCR-ABL negative chronic myeloproliferative neoplasms (MPNs).
Bruun, Niels Eske, Christensen, Sarah Friis, Cordua, Sabrina, Egyed, Miklos, Eickhardt-Dalbøge, Christina Schjellerup, Ellervik, Christina, Hasselbalch, Hans Carl, Kjaer, Lasse, Knudsen, Trine Alma, Kristiansen, Marie Hvelplund, Kruse, Torben A., Larsen, Morten Kranker, Lindholm, Matias Greve, Lindholt, Jes Sanddal, März, Winfried, Nielsen, Claus Henrik, Skov, Vibe, Sørensen, Anders Lindholm, Thomassen, Mads, Wienecke, Troels   +19 more
core   +1 more source

Clonal Hematopoiesis Risk Score and All-Cause and Cardiovascular Mortality in Older Adults [PDF]

IMPORTANCE: Clonal hematopoiesis (CH) with acquired pathogenic variants in myeloid leukemia driver genes is common in older adults but of unknown prognostic value. OBJECTIVE: To investigate the prevalence of CH and the utility of the CH risk score (CHRS)
Ballantyne, Christie M.,, Bick, Alexander G.,, Ebert, Benjamin L.,, Gondek, Lukasz,, Lund University., Natarajan, Pradeep,, Niroula, Abhishek,, Platz, Elizabeth A.,, Ru, Meng,, Saadatagah, Seyedmohammad,, Takahashi, Koichi,, Uddin, Md Mesbah,, Weeks, Lachelle D.,, Yu, Bing,   +13 more
core   +2 more sources

Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies [PDF]

, 2017
Allegra A. Petti, Amanda M. Smith, Angela M. Verdoni, Catrina Fronick, Celia V. Bangert, Christopher A. Miller, Christopher B. Cole, David A. Russler-Germain, Frith, Gue Su Chang, Jeffery M. Klco, Jeong, Mindy Guo, Nichole M. Helton, Poitras, Robert Fulton, Shamika Ketkar, Shelly O’Laughlin, Timothy J. Ley, Walter, Xi, Zheng   +21 more
core   +2 more sources

Clonal hematopoiesis of indeterminate potential and malignant neoplasms

Advances in Molecular Oncology
Clonal hematopoiesis of indeterminate potential (CHIP) is associated with aging and is a risk factor of many diseases including malignant neoplasms (MNPs). It originates through somatic mutations in hematopoietic stem and/or progenitor cells, promotes development of hematological MNPs and underlies unfavorable prognosis in solid malignant tumors ...
V. E. Shevchenko, T. I. Kushnir, M. V. Gudkova, N. E. Arnotskaya   +3 more
openaire   +1 more source

Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function [PDF]

We thank Clare A. Edward for technical assistance and Catherine M. Andary for being a second scorer for IF and histopathological analysis. We also thank Elsa N. Bou Ghanem and Manmeet Bhalla for their assistance with the neutrophil killing assays.
Archer, Stephen L, Bick, Alexander G, Bowdish, Dawn ME, Breznik, Jessica A, buttigieg, Marco M, Cook, Elina K, DeJong, Erica N, Dunham-Snary, Kimberly J, Hindmarch, Charles CT, Kennedy, Allison E, Luo, Yi Zhen, McNaughton, Amy JM, Mewburn, Jeffrey, Quin, Candice, Rauh, Michael J, Sadh, Sanathan, Vlasschaert, Caitlyn, Zhao, Kevin   +17 more
core   +1 more source

Hemothelium, Clonal Hematopoiesis of Indeterminate Potential, and Atherosclerosis [PDF]

Circulation, 2019
Abraham Aviv, Daniel Levy
openaire   +3 more sources

Clonal Hematopoiesis of Indeterminate Potential [PDF]

, 2020
openaire   +1 more source

Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing [PDF]

, 2020
Bangert, Celia V., Brune, Meryl K., Chang, Gue Su, Chen, David Y., Fronick, Catrina, Fulton, Robert S., George, Daniel R., Helton, Nichole M., Hoock, Mieke, Ketkar, Shamika, Leight, Elizabeth R., Ley, Timothy J., Miller, Christopher A., Petti, Allegra A., Ramakrishnan, Sai Mukund, Smith, Amanda M., Spencer, David H., Verdoni, Angela M.   +17 more
core   +1 more source