Results 31 to 40 of about 248,407 (299)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evaluation of Thompson Seedless and its Clone Based on Fruit Characteristics under Indian Condition

International Journal of Bio-Resource and Stress Management
The present study was conducted during fruiting season during October, 2023 to April, 2024 at the experimental farm of ICAR-National Research Centre for Grapes, Pune, Maharashtra, India to evaluate clones for fruit morphology by multivariate analysis ...
R. D. Nale, R. G. Somkuwar, I. D. Ghatul, Saklain Mulani   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

RFID Technology for Clonal Selection Purposes

Advances in horticultural science, 2010
Electronic barcodes based on radiofrequency identification (RFID) technology can be used in plant pathology to keep track of the sample identification. Moreover, phenotypic, environmental and genomical data could be added to RFID tags associated with the assayed plant.
Pagano, M., Bandinelli, R., Rinaldelli, E., Panattoni, A., Triolo, E., LUVISI, ANDREA   +5 more
openaire   +5 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Kin Recognition in a Clonal Fish, Poecilia formosa.

PLoS ONE, 2016
Relatedness strongly influences social behaviors in a wide variety of species. For most species, the highest typical degree of relatedness is between full siblings with 50% shared genes.
Amber M Makowicz, Ralph Tiedemann, Rachel N Steele, Ingo Schlupp   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Anergy in self-directed B lymphocytes from a statistical mechanics perspective

, 2012
The ability of the adaptive immune system to discriminate between self and non-self mainly stems from the ontogenic clonal-deletion of lymphocytes expressing strong binding affinity with self-peptides.
Agliari, Elena, Barra, Adriano, Del Ferraro, Gino, Guerra, Francesco, Tantari, Daniele   +4 more
core   +1 more source

Experimental evolution reveals high insecticide tolerance in Daphnia inhabiting farmland ponds [PDF]

, 2015
Exposure of nontarget populations to agricultural chemicals is an important aspect of global change. We quantified the capacity of natural Daphnia magna populations to locally adapt to insecticide exposure through a selection experiment involving ...
Agra, Agra, Angel, Barata, Carriere, Cerbin, Colbourne, Coors, Crawley, De Meester, Decaestecker, Declerck, Goussen, Hebert, Hoffman, Jansen, Kerr, Klüttgen, Lampert, Levinton, McCullagh, Medina, Messiaen, Miner, Muyssen, Naddy, Parker, Raymond, Saro, Sibly, Tanaka, Van Doorslaer, Van Doorslaer, Van Straalen, Walker, Waterfield, Wheeler   +36 more
core   +2 more sources