Results 31 to 40 of about 55,715 (309)

Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer. [PDF]

, 2017
Recent genomic analyses have revealed substantial tumor heterogeneity across various cancers. However, it remains unclear whether and how genomic heterogeneity is constrained during tumor evolution.
Bivona, Trever G, Cai, Mei-Chun, Chen, Hong-Zhuan, Chen, Minjiang, Fu, Yujie, Gao, Wei-Qiang, Gu, Zhenyu, Jing, Ying, Ma, Pengfei, Shen, Ying, Wang, Mengzhao, Wu, Jie, Yan, Ying, Zhang, Shengzhe, Zhao, Xiaojing, Zhu, Liang, Zhuang, Guanglei   +16 more
core   +2 more sources

Characterisation of Campylobacter spp. Isolated from Poultry in KwaZulu-Natal, South Africa

Antibiotics, 2020
This study investigated the antibiotic resistance, virulence profiles, and clonality of Campylobacter jejuni and Campylobacter coli isolated from an intensive poultry farming system in KwaZulu-Natal, South Africa. Following ethical approval, samples were
Stephanie Pillay, Daniel G. Amoako, Akebe L. K. Abia, Anou M. Somboro, Christiana O. Shobo, Keith Perrett, Linda A. Bester, Sabiha Y. Essack   +7 more
doaj   +1 more source

Using somatic mutation data to test tumors for clonal relatedness

, 2015
A major challenge for cancer pathologists is to determine whether a new tumor in a patient with cancer is a metastasis or an independent occurrence of the disease.
Begg, Colin B., Ostrovnaya, Irina, Seshan, Venkatraman E.   +2 more
core   +1 more source

Patients with Essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis [PDF]

, 2002
A significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life.
Carr, P., Dave, M., Donohoe, S., Harrison, C.N., Machin, S.J., Mackie, I.   +5 more
core   +1 more source

Genomic landscapes and clonality of de novo AML [PDF]

, 2013
No abstract ...
Brewin, John, Chevassut, Timothy, Horne, Gillian   +2 more
core   +1 more source

A Persisting Nontropical Focus of Burkholderia pseudomallei with Limited Genome Evolution over Five Decades

mSystems, 2020
Burkholderia pseudomallei is the causative agent of the high-mortality disease melioidosis. Although melioidosis is classified as a tropical disease, rare autochthonous cases have been reported from temperate climatic regions, with uncertainty as to ...
Jessica R. Webb, Nicky Buller, Audrey Rachlin, Clayton Golledge, Derek S. Sarovich, Erin P. Price, Mark Mayo, Bart J. Currie   +7 more
doaj   +1 more source

Conservation Genetics of the Endangered Lompoc Yerba Santa (Eriodictyon capitatum Eastw., Namaceae), including Phylogenomic Insights into the Evolution of Eriodictyon

Plants, 2023
Eriodictyon capitatum (Namaceae) is a narrowly distributed shrub endemic to western Santa Barbara County, where it is known from only 10 extant California Natural Diversity Database element occurrences (EOs).
C. Matt Guilliams, Kristen E. Hasenstab-Lehman   +1 more
doaj   +1 more source

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching, Chen, Irwin, Chong, Su, Hamburger, Agi, Jess, Philip, Jorgolli, Marsela, Le, Kim, Lin, Fen-Fen, Miranda, Les P, Mock, Marissa, Munro, Trent, Nevill, Tanner, Stevens, Jennitte, Tagari, Philip, Tan, Christopher, Winters, Aaron, Wu, Ming, Xu, Han   +17 more
core   +1 more source

Novel Multiplex PCR Method and Genome Sequence-Based Analog for High-Resolution Subclonal Assignment and Characterization of Escherichia coli Sequence Type 131 Isolates

Microbiology Spectrum, 2022
Escherichia coli sequence type 131 (ST131) is a pandemic, multidrug-resistant extraintestinal pathogen. The multiple distinctive ST131 subclones differ for rfb and fliC alleles (O and H antigens), fimH allele (type-1 fimbriae adhesin), resistance ...
Brian D. Johnston, David M. Gordon, Samantha Burn, Timothy J. Johnson, Bonnie P. Weber, Elizabeth A. Miller, James R. Johnson   +6 more
doaj   +1 more source

Emerging PCR-based techniques to study HIV-1 reservoir persistence [PDF]

, 2020
While current antiretroviral therapies are able to halt HIV-1 progression, they are not curative, as an interruption of treatment usually leads to viral rebound.
Cole, Basiel, Lambrechts, Laurens, Rutsaert, Sofie, Trypsteen, Wim, Vandekerckhove, Linos   +4 more
core   +2 more sources