Results 261 to 270 of about 790,447 (335)

Histone acetylation homeodynamics navigates cell survival and apoptosis. [PDF]

Nat Commun
Li K, Tian L, Cao W, Zhang J, Zhang W, Lin T, Huang S, Qiu Y, Ruan Z, Deng J, Long S, Palli SR, Li S.   +12 more
europepmc   +1 more source

Clonal characterization of bone marrow derived stem cells and their application for bone regeneration [PDF]

, 2010
Yin Xiao, Shobha Mareddy, Ross Crawford
openalex  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Unveiling Intra-Clonal Diversity of Monkeypox Virus from Brazil's First Outbreak Wave. [PDF]

Viruses
Witt ASA, Carvalho JVRP, Mamede I, Adelino TER, Iani FCM, Lima MT, Arantes TS, Cunha DES, Rodrigues RAL, Trindade GS, Kroon EG, Arias NEC, Franco GR, Abrahão JS.   +13 more
europepmc   +1 more source

Clonality analysis of neuroendocrine cells in gastric adenocarcinoma

, 2013
Lingling Wang
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

DNA prime and peptide boost immunization elicits robust neoantigen-specific CD8 ⁺ T cell responses and therapeutic protection in mouse tumor models. [PDF]

Oncoimmunology
Morgado-Cáceres P, Hofmann-Vega F, Figueroa D, Saavedra-Almarza J, Gálvez-Cancino F, Díaz X, Menares E, Roa E, Hidalgo S, Varas-Godoy M, Borgna V, Lladser A.   +11 more
europepmc   +1 more source

Deficient cytidine monophospho-N-acetylneuraminic acid: glycoprotein sialyltransferase activity in a clone of KB cells with altered cell fusion ability.

, 1983
S Toyama, A. Hajime Koyama, S Toyama
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source