Results 71 to 80 of about 750,149 (308)

The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement [PDF]

, 2012
AIR9 is a cytoskeleton-associated protein in Arabidopsis thaliana with roles in cytokinesis and cross wall maturation, and reported homologues in land plants and excavate protists, including trypanosomatids.
Almeida Costa, Cristina, Gibson, Wendy, Hammarton, Tansy, May, Sophie, Peacock, Lori, Robinson, Derrick, Robinson, Derrick R, Tetley, Laurence   +7 more
core   +3 more sources

Cloning human stem cells [PDF]

Canadian Medical Association Journal, 2004
![Figure][1] Figure. Photo by: Myra Rudakewich Pluripotent human embryonic stem cells have a unique ability to differentiate into any cell line. Although this has raised hopes that transplantation of stem cells may halt or reverse degenerative disorders such as diabetes and Parkinson ...
openaire   +2 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

miR-513b-5p inhibits the proliferation and promotes apoptosis of retinoblastoma cells by targeting TRIB1

Open Medicine, 2021
MicroRNAs are involved in the pathogenesis of various human malignant tumors. This study aims to explore the role of miR-513b-5p in the malignant proliferation of retinoblastoma (RB) cells and its potential molecular mechanisms.
Zhang Li-Juan, Wang Fang, Qi Pei-Yan, Zhou Wei-Yan, Wang Bing   +4 more
doaj   +1 more source

Hydra tropomyosin TROP1 is expressed in head-specific epithelial cells and is a major component of the cytoskeletal structure that anchors nematocytes [PDF]

, 1994
A cDNA clone encoding a 253 amino acid tropomyosin was isolated from Hydra in a differential screen for headspecific genes. The Hydra tropomyosin gene, designated trop1, is a single copy gene, lacks introns and is strongly expressed in tentacle-specific ...
Bosch, Thomas C. G., David, Charles N., Lopez de Haro, Maria S., Salgado, Luis M.   +3 more
core  

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout

Experimental and Molecular Medicine
Hypoimmunogenic universal induced pluripotent stemn (iPS) cells were generated through the targeted disruption of key genes, including human leukocyte antigen (HLA)-A, HLA-B and HLA-DR alpha (DRA), using the CRISPR–Cas9 system.
Juryun Kim, Yoojun Nam, Doyeong Jeon, Yujin Choi, SeonJu Choi, Chang Pyo Hong, Siyoung Kim, Hyerin Jung, Narae Park, Yeowon Sohn, Yeri Alice Rim, Ji Hyeon Ju   +11 more
doaj   +1 more source

Characterization of HTLV-1 Infectious Molecular Clone Isolated from Patient with HAM/TSP and Immortalization of Human Primary T-Cell Lines

Viruses
Human T-cell leukemia virus (HTLV-1) is the etiological agent of lymphoproliferative diseases such as adult T-cell leukemia and T-cell lymphoma (ATL) and a neurodegenerative disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM ...
Marcia Bellon, Pooja Jain, Christophe Nicot   +2 more
doaj   +1 more source

Alterations in integrin expression modulates invasion of pancreatic cancer cells

Journal of Experimental & Clinical Cancer Research, 2009
Background Factors mediating the invasion of pancreatic cancer cells through the extracellular matrix (ECM) are not fully understood. Methods In this study, sub-populations of the human pancreatic cancer cell line, MiaPaCa-2 were established which ...
Crown John, Clynes Martin, Walsh Naomi, O'Donovan Norma   +3 more
doaj   +1 more source

Prognostic Biomarker NUMB Is Inhibited by Breast Cancer Cell Exosomes to Promote Breast Cancer Progression

Journal of Immunology Research, 2022
Objective. To clarify the regulation of breast cancer cell-derived exosomes on breast cancer and the expression of the NUMB endocytic adaptor protein (NUMB) protein. Methods. The exosomes of breast cancer cell line MDA-MB-231 were isolated.
Xue Qin, Youde Cao
doaj   +1 more source