Results 231 to 240 of about 1,799,485 (379)

Clone conflict [PDF]

Nature Reviews Cancer, 2020
openaire   +2 more sources

Recombinant Laccase: I. Enzyme cloning and characterization [PDF]

, 2012
Claudio Nicolini, Debora Bruzzese, Maria Teresa Cambria, Nicola Luigi Bragazzi, Eugenia Pechkova   +4 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Bottleneck size drives the evolution of cooperative traits in an aggregative multicellular myxobacterium. [PDF]

PLoS Biol
Kalathera J, Jaiswal P, Mandal N, Patel V, Guttal V, Krishna S, Pande S.   +6 more
europepmc   +1 more source

Cloning, sequencing and expression of the lipase gene from Pseudomonas fragi IFO‐12049 in E. coli [PDF]

, 1988
Shigeyuki Aoyama, Naoyuki Yoshida, S Inouye   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Fermentation and clone selection modulate the biochemical and nutritional profile of cocoa beans grown in the southwestern Amazon. [PDF]

Sci Rep
Traspadini EIF, de Mello Prado R, Reis EG, Gratão PL, Wadt PGS, Ribeiro SB, da Silva DMP.   +6 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Streamlined rAAV HeLaS3 producer cell line generation via GS selection. [PDF]

Sci Rep
Antunes M, Moura F, Sebastian IR, Alves P, Gomes-Alves P, Escandell JM.   +5 more
europepmc   +1 more source

Cloning questions [PDF]

Nature Genetics, 1997
openaire   +2 more sources