The Determinants of Negotiated Pharmaceutical Prices
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert +2 more
wiley +1 more source
Examining the Influence of Glycemic Management During Sleep on Sleep‐Related Bruxism: A Pilot Study
Stabilisation of blood glucose levels during sleep may improve sleep‐related bruxism (SRB), particularly by suppressing sympathetic nervous system activity. Furthermore, it is expected that these findings will lead to the establishment of new treatment methods for SRB in sleep dentistry.
Tatsuya Taniwaki +5 more
wiley +1 more source
Practice Guideline Recommendations Summary: Treatment of Tics in People with Tourette Syndrome and Chronic Tic Disorders [PDF]
Objective To make recommendations on the assessment and management of tics in people with Tourette syndrome and chronic tic disorders. Methods A multidisciplinary panel consisting of 9 physicians, 2 psychologists, and 2 patient representatives ...
Cavanna, Andrea E. +12 more
core +2 more sources
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard +29 more
wiley +1 more source
Quality of Postoperative Pain Management after Midfacial Fracture Repair—An Outcome-oriented Study [PDF]
Objectives There is a lack of literature regarding the procedure-specific quality of acute postoperative pain management after midfacial fracture repair.
Djedovic, Gabriel +8 more
core +2 more sources
Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter +5 more
core +2 more sources
Abstract This case report describes two dogs exhibiting severe behavioural problems, both diagnosed with early‐life giardiasis and raised in environments lacking adequate maternal care and socialisation. Both dogs experienced chronic gastrointestinal and dermatological issues, as well as prolonged early‐life stress, which likely contributed to ...
Daniëlle Hartman +3 more
wiley +1 more source
Predicting drug penetration across the blood-brain barrier: comparison of different stationary phases for immobilized artificial membrane liquid chromatography [PDF]
Several in vitro methods have been tested for their ability to predict drug penetration across the blood-brain barrier into the central nervous system. In this article, the performance of three stationary phases for immobilized artificial membrane (IAM ...
De Vrieze, Mike +4 more
core
Successful private–public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines [PDF]
The European Paediatric Regulation mandated the European Commission to fund research on off-patent medicines with demonstrated therapeutic interest for children.
Baiardi, P +17 more
core +1 more source
Passionflower in the treatment of opiates withdrawal: a double blind and randomized controled trial
Clonidine-base detoxification has been utilized as the main protocol for several years However, detoxification with clondine has its limitation, including lack of efficacy for mental symptoms.
+4 more
doaj

