Results 91 to 100 of about 60,520 (264)

Quantitative assessment of cell fate decision between autophagy and apoptosis [PDF]

, 2017
Autophagy and apoptosis are cellular processes that regulate cell survival and death, the former by eliminating dysfunctional components in the cell, the latter by programmed cell death.
Bahar, Ivet, Bayir, Hulya, Liu, Bing, Oltvai, Zoltan N, Pak, Stephen C, Perlmutter, David H, Silverman, Gary A   +6 more
core   +3 more sources

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva, Maria Gabriely de Lima Silva, Eduardo S. Silva, Lucas Yure S. Silva, Renata Torres Pessoa, Silvio C. Alves‐Júnior, Jullyana S. S. Quintans, Laurent Picot, Irwin Rose A. Menezes, Lucindo J. Quintans‐Júnior   +9 more
wiley   +1 more source

A case report of clonidine induced syncope: a review of central actions of an old cardiovascular drug

BMC Pharmacology and Toxicology, 2018
Background Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
Alexander J. Sandweiss, Christopher M. Morrison, Anne Spichler, John Rozich   +3 more
doaj   +1 more source

Wurster fluidised bed coating of microparticles: Towards scalable production of oral sustained-release liquid medicines for patients with swallowing difficulties [PDF]

, 2019
© 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium ...
Craig Richardson, Liu, Fang, Mohylyuk, Valentyn, Murnane, Darragh, Patel, Kavil, Scott, Nathan   +5 more
core   +2 more sources

Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack of guidelines and good quality clinical studies on pain management has led
Hanna Sariola, Maija‐Liisa Kalliomäki, Heikki Kiiski, Essi Raatikainen, Juhana Frösen, Matti Reinikainen, Hanna Savioja, Kirsten Møller, Terhi Lohela, Riikka Takala, Martin Sigurdsson, Luis Romundstad, Stig Dyrskog, Karsten Bülow, Johanna Hästbacka   +14 more
wiley   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep–wake disturbances frequently occur at early stages of Alzheimer's disease (AD) and accelerate disease progression, but the underlying neural mechanisms are not fully understood. METHODS We examined sleep–wake behavior and locus coeruleus (LC) activity in young 5xFAD mice using electrophysiology and pharmacological approaches
Yi‐Ci Zhang, Xue‐Ting Zhang, Peng‐Yue Chen, Zi‐Yue Zhou, Mao‐Qing Huang, Kai‐Wen He   +5 more
wiley   +1 more source

Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]

, 2011
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter, Miotto, Karen, Mooney, Larissa, Nielsen, Suzanne, Torrington, Matthew, Zhao, Min   +5 more
core   +2 more sources

RVLM C1 Neurons Innervate Sacral as well as Thoracolumbar Autonomic Preganglionic Neurons in the Rat

Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.
Axons expressing the adrenaline‐synthesizing enzyme, phenylethanolamine N‐methyltransferase (PNMT), project widely throughout the spinal cord. Many of these axons are from C1 neurons of the rostral ventrolateral medulla. We confirm that dense arrays of PNMT‐expressing, C1‐derived axons surround thoracolumbar sympathetic preganglionic neurons, many of ...
I. J. Llewellyn‐Smith, L. Travis, A. A. Connelly, J. K. Bassi, C. Menuet, A. M. Allen   +5 more
wiley   +1 more source

Clonidine as an adjuvant to hyperbaric bupivacaine for spinal anesthesia in elderly patients undergoing lower limb orthopedic surgeries

Saudi Journal of Anaesthesia, 2014
Background: In elderly patients, use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This study tested the hypothesis that addition of small doses of clonidine augments the spinal
Deepti Agarwal, Manish Chopra, Medha Mohta, Ashok Kumar Sethi   +3 more
doaj   +1 more source