Results 111 to 120 of about 32,465 (232)
Dose-response curves for clonidine-produced analgesia in rats were constructed using the tail-flick and formalin tests. Subsequently, the relative role of alpha 1 and alpha 2 receptors in clonidine analgesia in each of these tests was determined using ...
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Pain Practice, Volume 26, Issue 8, November 2026.ABSTRACT Background Preoperative risk stratification to identify patients who develop acute refractory pain after lumbar spine surgery is a first step to prevent unfavorable outcomes. In this study, we aimed to develop and internally validate a clinically relevant, multidimensional prediction rule for preoperative risk assessment.
Ilse H. van de Wijgert +6 more
wiley +1 more source
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
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Response : Identifying Clonidine-Displacing Substance
, 1994 Response : Identifying Clonidine-Displacing ...
G Li (4638658) +4 more
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Effects of clonidine and morphine on opioid withdrawal in rhesus monkeys
, 1986 Rhesus monkeys undergoing opioid withdrawal either due to withholding morphine administration for 14 h or due to administration of naloxone, were treated with either morphine or clonidine.
Katz, Jonathan L.
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, 1988 The present experiments were aimed at the behavioural effects of clonidine and the possible involvement of opiate systems therein. Previous work had shown that opiate antagonists could block the effects of clonidine on blood pressure.
M van den Buuse, W de Jong, H Henneveld
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Site of clonidine action to inhibit gut propulsion in mice: Demonstration of a central component
, 1989 The role of supraspinal, spinal and peripheral alpha-2 adrenoceptors in the regulation of gastrointestinal motility in mice was investigated using anatomically site specific administration of clonidine and adrenoceptor antagonists.
Jiang, Qi, 1957-
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Effects of Morphine and Clonidine in the Rotarod Sedation Assay.
, 2014 A. Rotarod retention was challenged by intrathecal morphine, clonidine or both. Morphine (•) and clonidine (▪) inhibited rotarod performance in a dose-dependent manner with similar potency.
Laura S. Stone (286609) +4 more
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, 2010 Clonidine, an α2-adrenergic agonist, has been demonstrated to produce significant analgesia and potentiate morphine analgesia. Endothelin (ETA) receptor antagonists have also been found to potentiate the antinociceptive response to morphine.
Shridhar V. Andurkar +4 more
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