Results 91 to 100 of about 47,301 (233)

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Intraspinal Drug Delivery Reservoir Refill Procedure by Non-Physician Clinicians: A Nation-Wide Survey of Training, Pocket Fill Experience, and Life-Long Learning Behaviors [PDF]

, 2016
Intraspinal drug delivery (IDD) is a safe and efficacious method used to deliver medications for the treatment of chronic neurologic disease that requires periodic reservoir refills that can place patients at risk for a rare, accidental but potentially ...
McGlothlen, Gail
core   +1 more source

The Determinants of Negotiated Pharmaceutical Prices

The Journal of Industrial Economics, EarlyView.
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert, Sebastian Linde, Brandon Norton   +2 more
wiley   +1 more source

Examining the Influence of Glycemic Management During Sleep on Sleep‐Related Bruxism: A Pilot Study

Journal of Oral Rehabilitation, EarlyView.
Stabilisation of blood glucose levels during sleep may improve sleep‐related bruxism (SRB), particularly by suppressing sympathetic nervous system activity. Furthermore, it is expected that these findings will lead to the establishment of new treatment methods for SRB in sleep dentistry.
Tatsuya Taniwaki, Kazuo Okura, Yoshitaka Suzuki, Toyoko Tajima, Akitomo Watanabe, Yoshizo Matsuka   +5 more
wiley   +1 more source

Clonidine as an adjuvant to hyperbaric bupivacaine for spinal anesthesia in elderly patients undergoing lower limb orthopedic surgeries

Saudi Journal of Anaesthesia, 2014
Background: In elderly patients, use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This study tested the hypothesis that addition of small doses of clonidine augments the spinal
Deepti Agarwal, Manish Chopra, Medha Mohta, Ashok Kumar Sethi   +3 more
doaj   +1 more source

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery [PDF]

, 2008
BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients.
Baraka, Anis, El-Katib, Mohamad, Kassem, Rida, Maaliki, Hilal, Nahleh, Nezih, Struys, Michel, Zeidan, Ahed   +6 more
core   +2 more sources

Evaluation of Guanfacine Prescribing Practices for Attention Deficit Hyperactive Disorder Management: A Retrospective Medical Records Within a Child Development Service

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Guanfacine is a second line option for management of Attention Deficit Hyperactive Disorder (ADHD) and can be prescribed adjunctively with stimulants or as monotherapy. This medical record review evaluated prescribing practices, vital sign changes over time, and client outcomes. Methods This retrospective medical record review examined 171
Oluwatomi Adeola Ibilola, Karen Redhead, Brad Jongeling   +2 more
wiley   +1 more source

A case report of clonidine induced syncope: a review of central actions of an old cardiovascular drug

BMC Pharmacology and Toxicology, 2018
Background Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
Alexander J. Sandweiss, Christopher M. Morrison, Anne Spichler, John Rozich   +3 more
doaj   +1 more source

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
core   +1 more source

Clinical Insights From a Case of Sifrim‐Hitz‐Weiss Syndrome With a CHD4 Variant: Expanding the Phenotypic Spectrum and Its Response to Growth Hormone Therapy

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1403-1410, June 2026.
ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang, Shuangzhong Chen, Guanping Dong, Suhong Yang, Ping Wang, Qiong Zhou, Pingping Wang   +6 more
wiley   +1 more source