Results 101 to 110 of about 80,603 (326)

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi   +4 more
wiley   +1 more source

Analgesic and antisympathetic effects of clonidine in burn patients, a randomized, double-blind, placebo-controlled clinical trial

open access: yesIndian Journal of Plastic Surgery, 2007
Objectives:Unlike most other Analgesic drugs, α2 adrenoceptor agonists are capable of producing analgesia. The aim of this study was to evaluate the Analgesic and antisympathetic effects of clonidine, an α2 adrenoceptor agonist in burn patients.Materials
Ostadalipour Abbas   +4 more
doaj   +1 more source

Intraoperative clonidine vs lidocaine on hemodynamic response to laryngoscopic intubation and immune function in gynecological surgeries

open access: yesAin Shams Journal of Anesthesiology, 2020
Background This prospective randomised double-blind study was carried out on forty patients American Society of Anesthesiologists (ASA) physical status I–II , aged 40–60 years, scheduled for elective abdominal gynecological surgeries under general ...
Sawsan Gaber Mohamed   +2 more
doaj   +1 more source

NMR study of the inclusion complexes of β-cyclodextrin with diphenhydramine, clonidine and tolperisone

open access: yesSN Applied Sciences, 2022
Forming complexes with β-cyclodextrin can enhance stability, dissolution rate, solubility, and bioavailability of an active pharmaceutical ingredient. In this study, the inclusion behavior between β-cyclodextrin (β-CD) and diphenhydramine, clonidine, and
Symbat Zhumakova   +8 more
doaj   +1 more source

Discriminating depression, physical and social anhedonia by neurotransmitter related challenge tests [PDF]

open access: yes, 2016
The aim of this study was to investigate, if anhedonia, a salient component of depression, shows similar response patterns to neurotransmitter challenge tests as depression, and if the two questionnaire based components Physical (PA) and Social (SA ...
Hennig, Juergen, Netter, Petra
core   +2 more sources

Comparison of dexmedetomidine and clonidine (α2 agonist drugs) as an adjuvant to local anaesthesia in supraclavicular brachial plexus block: A randomised double-blind prospective study

open access: yesIndian Journal of Anaesthesia, 2012
Background and Objectives: Alpha-2 agonists are mixed with local anaesthetic agents to extend the duration of spinal, extradural and peripheral nerve blocks.
S. Swami, V. Keniya, S. Ladi, R. Rao
semanticscholar   +1 more source

Challenges and Considerations in Manipulating Oral Dosage Forms in Paediatric Healthcare Settings: A Narrative Review

open access: yesActa Paediatrica, EarlyView.
A substantial proportion of oral drug administrations in children require manipulation due to the lack of age‐appropriate formulations. Common methods such as splitting, crushing, and dispersing tablets in fluids can compromise dose accuracy because of e.g., drug solubility.
M. Paulsson   +5 more
wiley   +1 more source

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

open access: yes, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source

The Use of miRNA Panel as a Growth Plate Marker of Short‐Term Response to GH

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Recombinant human growth hormone (GH) therapy shows variable growth responses in patients with growth hormone deficiency (GHD), highlighting the need for reliable biomarkers to predict individual sensitivity. Objective This study investigated circulating microRNAs (miRNAs) involved in growth plate regulation during GH therapy in ...
Caroline Rosa Pellicciari   +8 more
wiley   +1 more source

The effect of pretreatment with clonidine on propofol consumption in opium abuser and non-abuser patients undergoing elective leg surgery

open access: yesJournal of Research in Medical Sciences, 2012
Objective: Clonidine, an alpha-2 adrenergic agonist, increases the quality of perioperative sedation and analgesia with a few side effects. This study was designed to assess the effect of clonidine premedication on the anesthesics used for elective below
Morteza Jabbari Moghadam   +4 more
doaj  

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