Intraspinal Drug Delivery Reservoir Refill Procedure by Non-Physician Clinicians: A Nation-Wide Survey of Training, Pocket Fill Experience, and Life-Long Learning Behaviors [PDF]
, 2016 Intraspinal drug delivery (IDD) is a safe and efficacious method used to deliver medications for the treatment of chronic neurologic disease that requires periodic reservoir refills that can place patients at risk for a rare, accidental but potentially ...
McGlothlen, Gail
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Brazilian guideline for the treatment of patients with opioids dependence syndrome [PDF]
, 2004 There is a relatively low prevalence of opioid use in Brazil, particularly involving the non-medical use of codeine and opiate-containing syrups. However, opioid dependence syndrome shows a significant total impact on mortality and morbidity.
Andrade, Arthur Guerra De +7 more
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Anaesthesia, Volume 81, Issue 2, Page 274-287, February 2026.Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz +16 more
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Passionflower in the treatment of opiates withdrawal: a double blind and randomized controled trial
Journal of Medicinal Plants, 2002 Clonidine-base detoxification has been utilized as the main protocol for several years However, detoxification with clondine has its limitation, including lack of efficacy for mental symptoms.
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doaj
Evaluation of clonidine as an adjuvant to brachial plexus block and its comparison with tramadol
Journal of Anaesthesiology Clinical Pharmacology, 2017 Background and Aims: It has been reported that clonidine when used as an additive in a dose of 90 μg in adults increases the duration of peripheral nerve blocks.
Prakash Kelika, Jamkar Maya Arun
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Predicting drug penetration across the blood-brain barrier: comparison of different stationary phases for immobilized artificial membrane liquid chromatography [PDF]
, 2014 Several in vitro methods have been tested for their ability to predict drug penetration across the blood-brain barrier into the central nervous system. In this article, the performance of three stationary phases for immobilized artificial membrane (IAM ...
De Vrieze, Mike +4 more
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Prediction of the permeability of neutral drugs inferred from their solvation properties [PDF]
, 2015 Determination of drug absorption is an important component of the drug discovery and development process in that it plays a key role in the decision to promote drug candidates to clinical trials.
Milanetti, Edoardo +2 more
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Reflections on Consciousness in Intensive Care
Acta Paediatrica, Volume 115, Issue 2, Page 275-284, February 2026.ABSTRACT Evaluating consciousness in intensive care is pivotal to relieving suffering with analgesic or sedative drugs and in prognosis and diagnoses. The usual clinical perspective is to equate consciousness with responsiveness, assuming functional motor responses and sympathetic activity of the patient. Clinical diagnoses of coma may be wrong in more
Michael Broomé, Tiit Mathiesen
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Subarachnoid clonidine and trauma response in cardiac surgery with cardiopulmonary bypass
Revista Brasileira de Anestesiologia, 2014 Background and objectives: The intense trauma response triggered by cardiopulmonary bypass can lead to increased morbidity and mortality. The present study evaluated whether clonidine, a drug of the class of α-2 agonists, administered by spinal route ...
Claudia Gissi da Rocha Ferreira +1 more
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, 2018 PURPOSE OF REVIEW: The purpose of this review is to summarize the most up-to-date literature on bath-related headache, a rare disorder. RECENT FINDINGS: Initially described in middle-aged Asian women, it is now reported in a wider demographic.
Kumpinsky, Aliza, Nahas, Stephanie J.
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