Results 111 to 120 of about 80,603 (326)

Buprenorphine in Neonatal Abstinence Syndrome. [PDF]

open access: yes, 2018
Infants exposed in utero to opioids will demonstrate a withdrawal syndrome known as neonatal abstinence syndrome (NAS). Buprenorphine is a long-acting opioid with therapeutic use in medication-assisted treatment of opioid dependency in adults and ...
Kraft, Walter K.
core   +1 more source

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

open access: yesEpilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang   +8 more
wiley   +1 more source

Clonidine as an adjuvant to hyperbaric bupivacaine for spinal anesthesia in elderly patients undergoing lower limb orthopedic surgeries

open access: yesSaudi Journal of Anaesthesia, 2014
Background: In elderly patients, use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This study tested the hypothesis that addition of small doses of clonidine augments the spinal
Deepti Agarwal   +3 more
doaj   +1 more source

Hyperhidrosis: don't sweat it

open access: yesInternal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

Efficacy of Analgesic Effects of Low Dose Intrathecal Clonidine as Adjuvant to Bupivacaine

open access: yesIndian Journal of Anaesthesia, 2007
Clonidine (α-2-adrenergic agonist) has analgesic effect at spinal level mediated by postsynaptically situated α-2-adrenoreceptors in dorsal horn of spinal cord. Previous studies have used this drug intrathecally in higher dosages.
B S Sethi   +2 more
doaj  

Growth hormone stimulation test with Clonidine and Arginine an unreported side effect

open access: yesJournal of Clinical and Translational Endocrinology Case Reports, 2020
Clonidine is one of the commonly used pharmacological agents for growth hormone stimulation. It is considered generally safe, with only few non-serious reported side effects.
Renad AbdelNabi, Reem Al Khalifah
doaj  

A case report of clonidine induced syncope: a review of central actions of an old cardiovascular drug

open access: yesBMC Pharmacology and Toxicology, 2018
Background Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
Alexander J. Sandweiss   +3 more
doaj   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard   +2 more
wiley   +1 more source

Tyramine reveals failing α2-adrenoceptor control of catecholamine release and total peripheral vascular resistance in hypertensive rats [PDF]

open access: yes, 2013
α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension.
Berg, Torill, Jensen, Jørgen
core   +2 more sources

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