Results 121 to 130 of about 60,520 (264)

The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats [PDF]

open access: yes, 2014
Evidence suggests that noradrenergic signaling may play a role in mediating alcohol-drinking behavior in both rodents and humans. We have investigated this possibility by administering clonidine to alcohol-drinking rats selectively bred for alcohol ...
Alexander, Laura   +4 more
core   +1 more source

Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT A recent survey in the Philippines, PRESYON‐4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherence were 68% and 86%, respectively, the rate of BP control was low at 37%. Furthermore, there remained a high degree of unawareness
Deborah Ignacia D. Ona   +17 more
wiley   +1 more source

Functional bowel disease : a challenging frontier in gastroenterology [PDF]

open access: yes, 1999
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core  

Successful private–public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines [PDF]

open access: yes, 2014
The European Paediatric Regulation mandated the European Commission to fund research on off-patent medicines with demonstrated therapeutic interest for children.
Baiardi, P   +17 more
core   +1 more source

Effect of Antihypertensive Treatment on Hypotension, Mortality and Length of Stay in Orthopedic Trauma and First Detected High Blood Pressure Adults in a Large Urban Hospital: A Retrospective Cohort Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT Trauma is a frequent cause of hospital admission in adults, and while arterial hypertension is common in the general population, reactive hypertension associated with trauma remains poorly studied from a therapeutic perspective. This retrospective cohort study aimed to estimate the impact of antihypertensive treatment on hypotension occurrence,
Carlos José Atencia, Fabian Jaimes
wiley   +1 more source

Ketamine: NMDA receptors and beyond [PDF]

open access: yes, 2016
Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi   +2 more
core   +2 more sources

Ventricular tachycardia induced by clonidine withdrawal. [PDF]

open access: bronze, 1985
Susumu Nakagawa   +2 more
openalex   +1 more source

The role of BK potassium channels in analgesia produced by alpha-2 adrenergic receptors [PDF]

open access: yes, 2016
BACKGROUND AND OBJECTIVE: Millions of people suffer from pain worldwide, and annually, great economic costs are imposed on societies for pain relief. Analgesics such as alpha-2 adrenergic receptor agonists, which have low risk of complications, can be ...
Attarzadeh-Yazd, G.   +2 more
core   +1 more source

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