Results 61 to 70 of about 22,511 (192)
Equine Veterinary Education, EarlyView.Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly +4 more
wiley +1 more source
BMC Pharmacology and Toxicology, 2018 Background Clonidine is an imidazoline sympatholytic, acting on both α2-adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively.
Alexander J. Sandweiss +3 more
doaj +1 more source
Journal of Internal Medicine, EarlyView.Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily affects female patients. There are scarce data evaluating the long‐term outcomes in POTS. Objectives This study sought to evaluate the long‐term impacts of POTS over multiple decades in adult patients.
Kate M. Bourne +11 more
wiley +1 more source
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim This study aimed to analyse the pathways to obtaining a diagnosis of functional tic‐like behaviour (FTLBs) in the United Kingdom. Methods The primary caregivers of children with FTLB (n = 55) were recruited through charities and completed an anonymised survey.
Amanda K. Ludlow +4 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.ABSTRACT Dopaminergic medication used in disorders like Parkinson's disease (PD) and restless legs syndrome can cause impulsive‐compulsive behaviour (ICB), often with strong negative effects on patients' quality of life. This narrative review presents translational evidence on iatrogenic ICB, taking findings from epidemiological, clinical, neuroimaging
Mirjam Wolfschlag +7 more
wiley +1 more source
Saudi Journal of Anaesthesia, 2014 Background: In elderly patients, use of adjuvant with small doses of local anesthetics is a preferred technique for spinal anesthesia for lower limb surgeries. This study tested the hypothesis that addition of small doses of clonidine augments the spinal
Deepti Agarwal +3 more
doaj +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1403-1410, June 2026.ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang +6 more
wiley +1 more source
Intrathecal clonidine for perioperative pain relief in abdominal hysterectomy
Indian Journal of Pain, 2013 Background: Two different doses of intrathecal clonidine with hyperbaric bupivacaine fentanyl combination is compared in women undergoing abdominal hysterectomy to get best beneficial effects with minimal incidence of side effects/complications. Methods:
Debjyoti Dutta +4 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Brimonidine ingestion in young children can cause rapid, severe central nervous system (CNS) depression, including miosis and hypotonia. Clinicians should maintain a high index of suspicion in toddlers presenting with unexplained drowsiness following exposure.
Ramin Zareh Mahmoudabadi +6 more
wiley +1 more source
Passionflower in the treatment of opiates withdrawal: a double blind and randomized controled trial
Journal of Medicinal Plants, 2002 Clonidine-base detoxification has been utilized as the main protocol for several years However, detoxification with clondine has its limitation, including lack of efficacy for mental symptoms.
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