Results 51 to 60 of about 22,559 (187)

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Evaluation of Nalbuphine with that of Clonidine as an Adjuvant to IntraThecal 0.5% Hyperbaric Bupivacaine

National Board of Examinations Journal of Medical Sciences
Background and objectives: This study compares the clinical efficacy of nalbuphine and clonidine as adjuvants to 0.5% hyperbaric bupivacaine for Sub arachnoid block.
Vakkakula Kiran Kumar Reddy, B Manaswini, B Anusha, Kattamreddy Ananth Rupesh   +3 more
doaj   +1 more source

Impact of Respiratory Support Strategies on CO2 Variability During Therapeutic Hypothermia in Neonates With Asphyxia: Data From the German Hypothermia Registry

Acta Paediatrica, EarlyView.
ABSTRACT Aim To evaluate associations between respiratory support strategies, partial pressure of carbon dioxide (pCO2) variability and oxygen exposure in neonates with hypoxic–ischaemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Methods This retrospective multicentre study used data from the German Hypothermia Registry, including ...
Sebiha Demir, Anne Groteklaes, Bettina Bohnhorst, Kirsten Glaser, Andreas Müller, Hemmen Sabir, Till Dresbach, on behalf of the German Hypothermia Registry, Milian Brasche, Nicolas Allgaier, Daniel Klotz, Norbert Teig, Katja Schneider, Hemmen Sabir, Sandra Holz, Birte Tröger, Thorsten Körner, Uwe Höpner, Marie Schmenk, Michael Hofmann, Mario Rüdiger, Julia Osterholt, Martin Berghäuser, Christopher Willerscheidt, Farina Morgenroth, Hans Jörg Bittrich, Steven Hébert, Arber Arapi, Anja Stein, Veit Lange, Gunnar Rau, Lisa‐Marie Stoek, Nikolas Hillenbrand, Matthias Reger, Susanne Schade, Jana Dieks, Heimke von Osten, Marita Horstkemper, Martin Blohm, Mario Lange, Bettina Bohnhorst, Manuela Friederike Richter, Simon Kranig, Maurice Petrasch, Nasenien Nourkami‐Tutdibi, Christine Pinkwart, Thomas Kriebel, Silvia Welcker, Nora Bonney, Angela Kribs, Clemens Andrée, Sophia Stadermann, Kirsten Glaser, Peter Jahn, Katrin Braun, Anna Eisenhardt, Alba Perez‐Ortiz, Nadine Mand, Ines Wallot, Timea Takacs, Anja Jäger, Oliver Schroers, Esther Schouten, Claudia Nussbaum, Kai Böckenholt, Rüdiger Wentzell, Guido Engelmann, Katherine Louise Kastor, Michael Schroth, Matthias Engler, Friederike Eichhorn, Moritz Rohrbach, Fabian Bärtling, Frank Dohle, Matthias Keller, Marion Weber, Verena Lehnerer, Anja Mayer, Marie‐Claire Detemple, Valentin Oellers, Markus Pingel, Friederike Eilbracht, Jutta Adler, Elena Eberle, Karoline Goj, Virginia Toth, Andrea Czoske, Cornelia Wiechers, Christiane Mayer, Anja Schumann, Patrick Salaschek, Janaina Rauch, Kai Hensel, Pia Paul   +93 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

The effect of pretreatment with clonidine on propofol consumption in opium abuser and non-abuser patients undergoing elective leg surgery

Journal of Research in Medical Sciences, 2012
Objective: Clonidine, an alpha-2 adrenergic agonist, increases the quality of perioperative sedation and analgesia with a few side effects. This study was designed to assess the effect of clonidine premedication on the anesthesics used for elective below
Morteza Jabbari Moghadam, Davood Ommi, Alireza Mirkheshti, Mehdi Shadnoush, Ali Dabbagh   +4 more
doaj  

Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1‐Related Noonan Syndrome

Clinical Genetics, EarlyView.
This study illustrates the phenotypic variability of LZTR1‐related Noonan syndrome type 10 in two pediatric patients, including presentations without congenital heart defects. The findings emphasize the importance of whole‐exome sequencing and longitudinal re‐evaluation of variants of uncertain significance in achieving accurate diagnosis.
Karolina Skrzyńska, Barbara Kalina‐Faska, Ewa Błaszczyk, Aneta Gawlik‐Starzyk   +3 more
wiley   +1 more source

Effects of Preoperative Intravenous Clonidine in Patients Undergoing Cataract Surgery: A Double-Blind, Randomized Trial

Journal of Ophthalmology, 2014
Objectives. The aim of this study was to assess the effects of clonidine on intraoperative analgesia, sedation, intraocular and blood pressure, arrhythmia, and ischemia. Methods. Forty patients undergoing cataract surgery were allocated into two groups.
Ana Ellen Queiroz Santiago, Adriana Machado Issy, Rioko Kimiko Sakata   +2 more
doaj   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Efficacy of Analgesic Effects of Low Dose Intrathecal Clonidine as Adjuvant to Bupivacaine

Indian Journal of Anaesthesia, 2007
Clonidine (α-2-adrenergic agonist) has analgesic effect at spinal level mediated by postsynaptically situated α-2-adrenoreceptors in dorsal horn of spinal cord. Previous studies have used this drug intrathecally in higher dosages.
B S Sethi, Mary Samuel, Deepak Sreevastava   +2 more
doaj  

Clinical practices in the management of cervical Hansen type I intervertebral disc herniation among veterinary neurologists in North America and Europe

Journal of Small Animal Practice, EarlyView.
Objectives To describe current clinical practices in the management of cervical Hansen type I intervertebral disc herniation among American College of Veterinary Internal Medicine/European College of Veterinary Neurology neurologists. Materials and Methods An anonymous web‐based survey was distributed via professional listservs between October and ...
A. Mondino, M. Riobó, N. J. Olby, S. Moore, P. J. Early   +4 more
wiley   +1 more source